Regular season and playoffs
| Year | Team | Games | Att | Cmp | Cmp% | Pass Yds | Pass TD | INT | Sacks | Y/A | Rating |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2018 | CLE | 14 | 486 | 310 | 63.8 | 3725 | 27 | 14 | 25 | 7.7 | 93.7 |
| 2019 | CLE | 16 | 534 | 317 | 59.4 | 3827 | 22 | 21 | 40 | 7.2 | 78.8 |
| 2020 | CLE | 18 | 557 | 349 | 62.7 | 4030 | 30 | 9 | 27 | 7.2 | 95.7 |
| 2021 | CLE | 14 | 418 | 253 | 60.5 | 3010 | 17 | 13 | 43 | 7.2 | 83.1 |
| 2022 | LA | 12 | 335 | 201 | 60.0 | 2163 | 10 | 8 | 36 | 6.5 | 79.0 |
| 2023 | TB | 19 | 643 | 412 | 64.1 | 4730 | 34 | 12 | 48 | 7.4 | 96.0 |
| 2024 | TB | 18 | 588 | 422 | 71.8 | 4685 | 43 | 16 | 41 | 8.0 | 108.1 |
| 2025 | TB | 17 | 543 | 343 | 63.2 | 3693 | 26 | 11 | 36 | 6.8 | 90.6 |
| 2026 | TB | 4 | 107 | 68 | 63.6 | 679 | 3 | 2 | 13 | 6.3 | 83.0 |