Regular season and playoffs
| Year | Team | Games | Att | Cmp | Cmp% | Pass Yds | Pass TD | INT | Sacks | Y/A | Rating |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2011 | JAX | 15 | 413 | 210 | 50.8 | 2214 | 12 | 11 | 40 | 5.4 | 65.4 |
| 2012 | JAX | 10 | 278 | 162 | 58.3 | 1662 | 9 | 6 | 22 | 6.0 | 77.4 |
| 2013 | JAX | 3 | 86 | 42 | 48.8 | 481 | 1 | 7 | 12 | 5.6 | 36.0 |
| 2014 | SF | 1 | 7 | 3 | 42.9 | 38 | 1 | 0 | 0 | 5.4 | 100.0 |
| 2015 | SF | 8 | 282 | 178 | 63.1 | 2031 | 10 | 7 | 25 | 7.2 | 86.2 |
| 2016 | SF | 6 | 160 | 91 | 56.9 | 925 | 5 | 6 | 11 | 5.8 | 68.4 |
| 2017 | ARI | 5 | 171 | 95 | 55.6 | 1086 | 6 | 6 | 23 | 6.4 | 71.9 |
| 2018 | TEN | 8 | 101 | 61 | 60.4 | 626 | 4 | 4 | 5 | 6.2 | 74.9 |
| 2020 | TB | 4 | 16 | 9 | 56.2 | 143 | 2 | 0 | 1 | 8.9 | 125.8 |
| 2021 | TB | 6 | 11 | 7 | 63.6 | 67 | 0 | 0 | 1 | 6.1 | 80.5 |
| 2022 | TB | 1 | 8 | 6 | 75.0 | 29 | 1 | 0 | 0 | 3.6 | 119.3 |
| 2023 | KC | 2 | 35 | 18 | 51.4 | 185 | 0 | 3 | 1 | 5.3 | 31.2 |