Regular season and playoffs
| Year | Team | Games | Att | Cmp | Cmp% | Pass Yds | Pass TD | INT | Sacks | Y/A | Rating |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2009 | NE | 4 | 27 | 19 | 70.4 | 142 | 0 | 0 | 2 | 5.3 | 82.6 |
| 2010 | NE | 5 | 15 | 7 | 46.7 | 122 | 1 | 1 | 0 | 8.1 | 69.3 |
| 2011 | NE | 2 | 1 | 1 | 100.0 | 22 | 0 | 0 | 0 | 22.0 | 118.8 |
| 2012 | ARI | 2 | 53 | 30 | 56.6 | 330 | 1 | 2 | 4 | 6.2 | 65.8 |
| 2013 | CLE | 3 | 96 | 57 | 59.4 | 615 | 5 | 3 | 6 | 6.4 | 82.6 |
| 2014 | CLE | 14 | 438 | 242 | 55.3 | 3326 | 12 | 13 | 24 | 7.6 | 76.5 |
| 2015 | HOU | 12 | 403 | 239 | 59.3 | 2742 | 19 | 11 | 28 | 6.8 | 84.2 |
| 2016 | CHI | 6 | 200 | 134 | 67.0 | 1445 | 6 | 0 | 4 | 7.2 | 98.0 |
| 2017 | NE | 11 | 211 | 123 | 58.3 | 1287 | 4 | 4 | 16 | 6.1 | 74.5 |
| 2018 | NE | 5 | 2 | 1 | 50.0 | 7 | 0 | 0 | 0 | 3.5 | 58.3 |
| 2019 | IND | 4 | 65 | 35 | 53.8 | 372 | 4 | 4 | 5 | 5.7 | 65.7 |
| 2020 | NE | 1 | 24 | 15 | 62.5 | 130 | 0 | 1 | 2 | 5.4 | 59.4 |
| 2021 | NE | 5 | 11 | 9 | 81.8 | 227 | 1 | 0 | 0 | 20.6 | 149.1 |
| 2022 | NE | 1 | 6 | 5 | 83.3 | 37 | 0 | 0 | 1 | 6.2 | 92.4 |
| 2023 | LV | 2 | 42 | 23 | 54.8 | 231 | 0 | 2 | 1 | 5.5 | 50.8 |