Regular season and playoffs
| Year | Team | Games | Att | Cmp | Cmp% | Pass Yds | Pass TD | INT | Sacks | Y/A | Rating |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2016 | PHI | 16 | 607 | 379 | 62.4 | 3782 | 16 | 14 | 33 | 6.2 | 79.3 |
| 2017 | PHI | 13 | 440 | 265 | 60.2 | 3296 | 33 | 7 | 28 | 7.5 | 101.9 |
| 2018 | PHI | 11 | 401 | 279 | 69.6 | 3074 | 21 | 7 | 31 | 7.7 | 102.2 |
| 2019 | PHI | 17 | 611 | 389 | 63.7 | 4042 | 27 | 7 | 38 | 6.6 | 92.7 |
| 2020 | PHI | 12 | 437 | 251 | 57.4 | 2620 | 16 | 15 | 50 | 6.0 | 72.8 |
| 2021 | IND | 17 | 516 | 322 | 62.4 | 3563 | 27 | 7 | 32 | 6.9 | 94.6 |
| 2022 | WAS | 8 | 276 | 172 | 62.3 | 1755 | 11 | 9 | 26 | 6.4 | 80.2 |
| 2023 | LA | 1 | 24 | 17 | 70.8 | 163 | 2 | 1 | 2 | 6.8 | 99.8 |
| 2024 | KC | 2 | 19 | 12 | 63.2 | 118 | 0 | 0 | 4 | 6.2 | 80.6 |
| 2025 | MIN | 5 | 169 | 110 | 65.1 | 1216 | 6 | 5 | 19 | 7.2 | 85.8 |
| 2026 | MIN | 2 | 39 | 23 | 59.0 | 276 | 3 | 0 | 6 | 7.1 | 106.4 |