Regular season and playoffs
| Year | Team | Games | Att | Cmp | Cmp% | Pass Yds | Pass TD | INT | Sacks | Y/A | Rating |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2008 | MIA | 1 | 12 | 7 | 58.3 | 67 | 0 | 0 | 0 | 5.6 | 74.0 |
| 2009 | MIA | 14 | 451 | 274 | 60.8 | 2878 | 12 | 14 | 26 | 6.4 | 75.2 |
| 2010 | MIA | 15 | 491 | 302 | 61.5 | 3298 | 15 | 18 | 30 | 6.7 | 76.2 |
| 2011 | MIA | 4 | 112 | 64 | 57.1 | 868 | 4 | 4 | 11 | 7.8 | 79.0 |
| 2012 | JAX | 10 | 308 | 166 | 53.9 | 2084 | 11 | 11 | 28 | 6.8 | 72.2 |
| 2013 | JAX | 15 | 503 | 305 | 60.6 | 3241 | 13 | 14 | 38 | 6.4 | 76.5 |
| 2014 | JAX | 3 | 78 | 42 | 53.8 | 492 | 3 | 1 | 16 | 6.3 | 80.7 |
| 2017 | JAX | 2 | 2 | 0 | 0.0 | 0 | 0 | 0 | 0 | 0.0 | 39.6 |
| 2018 | KC | 1 | 3 | 2 | 66.7 | 29 | 0 | 0 | 0 | 9.7 | 97.9 |
| 2020 | KC | 4 | 46 | 34 | 73.9 | 314 | 2 | 1 | 3 | 6.8 | 97.6 |
| 2021 | KC | 4 | 16 | 11 | 68.8 | 82 | 0 | 0 | 0 | 5.1 | 80.7 |
| 2022 | KC | 4 | 9 | 5 | 55.6 | 23 | 1 | 0 | 0 | 2.6 | 97.9 |