Regular season and playoffs
| Year | Team | Games | Att | Cmp | Cmp% | Pass Yds | Pass TD | INT | Sacks | Y/A | Rating |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2017 | HOU | 7 | 204 | 126 | 61.8 | 1699 | 19 | 8 | 19 | 8.3 | 103.0 |
| 2018 | HOU | 17 | 554 | 374 | 67.5 | 4400 | 27 | 10 | 65 | 7.9 | 100.2 |
| 2019 | HOU | 17 | 572 | 384 | 67.1 | 4487 | 29 | 12 | 55 | 7.8 | 98.9 |
| 2020 | HOU | 16 | 544 | 382 | 70.2 | 4823 | 33 | 7 | 49 | 8.9 | 112.4 |
| 2022 | CLE | 6 | 170 | 99 | 58.2 | 1102 | 7 | 5 | 20 | 6.5 | 79.1 |
| 2023 | CLE | 6 | 171 | 105 | 61.4 | 1115 | 7 | 4 | 17 | 6.5 | 84.3 |
| 2024 | CLE | 7 | 216 | 137 | 63.4 | 1148 | 5 | 3 | 33 | 5.3 | 79.0 |
| 2026 | CLE | 7 | 210 | 136 | 64.8 | 1482 | 7 | 3 | 25 | 7.1 | 90.6 |