Regular season and playoffs
| Year | Team | Games | Att | Cmp | Cmp% | Pass Yds | Pass TD | INT | Sacks | Y/A | Rating |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2012 | PHI | 7 | 265 | 161 | 60.8 | 1699 | 6 | 5 | 20 | 6.4 | 79.1 |
| 2013 | PHI | 14 | 350 | 226 | 64.6 | 3086 | 29 | 2 | 30 | 8.8 | 117.9 |
| 2014 | PHI | 8 | 311 | 186 | 59.8 | 2163 | 13 | 10 | 9 | 7.0 | 81.4 |
| 2015 | LA | 11 | 337 | 190 | 56.4 | 2052 | 7 | 10 | 14 | 6.1 | 69.0 |
| 2016 | KC | 2 | 55 | 36 | 65.5 | 410 | 3 | 0 | 4 | 7.5 | 105.9 |
| 2017 | PHI | 10 | 207 | 134 | 64.7 | 1508 | 11 | 3 | 7 | 7.3 | 98.1 |
| 2018 | PHI | 7 | 266 | 184 | 69.2 | 1880 | 10 | 8 | 10 | 7.1 | 89.2 |
| 2019 | JAX | 4 | 117 | 77 | 65.8 | 736 | 3 | 2 | 8 | 6.3 | 84.6 |
| 2020 | CHI | 9 | 312 | 202 | 64.7 | 1852 | 10 | 8 | 18 | 5.9 | 80.8 |
| 2021 | CHI | 1 | 35 | 24 | 68.6 | 250 | 1 | 0 | 4 | 7.1 | 98.5 |
| 2022 | IND | 2 | 42 | 25 | 59.5 | 225 | 0 | 4 | 8 | 5.4 | 34.4 |