Regular season and playoffs
| Year | Team | Games | Att | Cmp | Cmp% | Pass Yds | Pass TD | INT | Sacks | Y/A | Rating |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2012 | MIA | 16 | 484 | 282 | 58.3 | 3294 | 12 | 13 | 35 | 6.8 | 76.1 |
| 2013 | MIA | 16 | 588 | 355 | 60.4 | 3913 | 24 | 17 | 58 | 6.7 | 81.7 |
| 2014 | MIA | 16 | 590 | 392 | 66.4 | 4045 | 27 | 12 | 46 | 6.9 | 92.8 |
| 2015 | MIA | 16 | 586 | 363 | 61.9 | 4208 | 24 | 12 | 45 | 7.2 | 88.7 |
| 2016 | MIA | 13 | 389 | 261 | 67.1 | 2995 | 19 | 12 | 29 | 7.7 | 93.5 |
| 2018 | MIA | 11 | 274 | 176 | 64.2 | 1979 | 17 | 9 | 35 | 7.2 | 92.7 |
| 2019 | TEN | 15 | 346 | 237 | 68.5 | 3111 | 27 | 7 | 36 | 9.0 | 114.2 |
| 2020 | TEN | 17 | 507 | 333 | 65.7 | 3984 | 34 | 8 | 25 | 7.9 | 105.3 |
| 2021 | TEN | 18 | 555 | 372 | 67.0 | 3954 | 22 | 17 | 48 | 7.1 | 88.1 |
| 2022 | TEN | 12 | 325 | 212 | 65.2 | 2536 | 13 | 6 | 33 | 7.8 | 94.6 |
| 2023 | TEN | 9 | 230 | 149 | 64.8 | 1616 | 4 | 7 | 32 | 7.0 | 78.5 |