Franchise 32 seasons 229–277–1 all-time 9 playoff trips 0 Super Bowls
2008 players
Passing
| Jake Delhomme | 414 | 246 | 3,284 | 15 | 12 | 7.9 |
Rushing
| DeAngelo Williams | 274 | 1,518 | 18 | 5.5 |
| Jonathan Stewart | 183 | 835 | 10 | 4.6 |
| Steve Smith | 5 | 40 | 0 | 8.0 |
| Jake Delhomme | 20 | 21 | 2 | 1.0 |
| Brad Hoover | 9 | 18 | 0 | 2.0 |
| Nick Goings | 9 | 10 | 0 | 1.1 |
| Josh McCown | 4 | -3 | 0 | -0.8 |
Receiving
| Steve Smith | 0 | 78 | 1,417 | 6 | 1417.0 |
| Muhsin Muhammad | 0 | 65 | 923 | 5 | 923.0 |
| Dante Rosario | 0 | 18 | 209 | 1 | 209.0 |
| Jeff King | 0 | 21 | 195 | 1 | 195.0 |
| D.J. Hackett | 0 | 13 | 181 | 0 | 181.0 |
| DeAngelo Williams | 0 | 22 | 121 | 2 | 121.0 |
| Dwayne Jarrett | 1 | 10 | 119 | 0 | 119.0 |
| Jonathan Stewart | 0 | 8 | 47 | 0 | 47.0 |
| Brad Hoover | 0 | 6 | 39 | 0 | 39.0 |
| Mark Jones | 0 | 2 | 32 | 0 | 32.0 |
| Nick Goings | 0 | 3 | 1 | 0 | 1.0 |
Defense
| Jon Beason | MLB | 118 | 90 | 0.0 | 3 | 8 | 0 |
| Thomas Davis | OLB | 106 | 85 | 3.5 | 0 | 6 | 2 |
| Chris Gamble | CB | 87 | 77 | 0.0 | 3 | 18 | 1 |
| Richard Marshall | CB | 71 | 64 | 2.0 | 1 | 4 | 0 |
| Chris Harris | DB | 63 | 53 | 0.0 | 1 | 3 | 2 |
| Charles Godfrey | FS | 54 | 45 | 1.0 | 1 | 5 | 1 |
| Ken Lucas | CB | 54 | 47 | 0.0 | 2 | 10 | 0 |
| Julius Peppers | DE | 47 | 36 | 14.5 | 0 | 5 | 5 |
| Na'il Diggs | LB | 46 | 35 | 1.0 | 1 | 2 | 0 |
| Damione Lewis | DT | 34 | 24 | 3.5 | 0 | 5 | 1 |
| Tyler Brayton | DT | 33 | 28 | 4.5 | 0 | 3 | 1 |
| Ma'ake Kemoeatu | NT | 32 | 27 | 0.0 | 0 | 2 | 1 |
| Charles Johnson | DE | 23 | 18 | 6.0 | 0 | 7 | 1 |
| Landon Johnson | MLB | 16 | 14 | 0.0 | 0 | 0 | 1 |
| Nick Goings | RB | 12 | 9 | 0.0 | 0 | 0 | 0 |
| Donte Curry | LB | 12 | 10 | 0.0 | 0 | 0 | 0 |
| Darwin Walker | DT | 9 | 5 | 0.0 | 0 | 2 | 0 |
| Gary Gibson | DT | 9 | 5 | 0.0 | 0 | 0 | 0 |
| Dante Wesley | DB | 8 | 7 | 0.0 | 0 | 3 | 1 |
| Nate Salley | DB | 7 | 5 | 0.0 | 0 | 0 | 0 |
| Quinton Teal | DB | 6 | 5 | 0.0 | 0 | 0 | 0 |
| Hilee Taylor | DE | 4 | 4 | 1.0 | 0 | 0 | 0 |
| Dan Connor | ILB | 4 | 4 | 0.0 | 0 | 0 | 0 |
| Brad Hoover | FB | 4 | 4 | 0.0 | 0 | 0 | 0 |
| Steve Smith | WR | 4 | 4 | 0.0 | 0 | 0 | 0 |
| Dante Rosario | TE | 4 | 4 | 0.0 | 0 | 0 | 0 |
| Jason Kyle | LS | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Nick Hayden | DT | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Gary Barnidge | TE | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Jonathan Stewart | RB | 3 | 3 | 0.0 | 0 | 0 | 0 |
| DeAngelo Williams | RB | 2 | 2 | 0.0 | 0 | 0 | 0 |
| James Anderson | OLB | 2 | 2 | 0.0 | 0 | 0 | 0 |
| C.J. Wilson | DB | 2 | 2 | 0.0 | 0 | 1 | 0 |
| Adam Seward | LB | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Rhys Lloyd | K | 2 | 1 | 0.0 | 0 | 0 | 0 |
| Muhsin Muhammad | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jason Baker | P | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jeremy Bridges | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Mark Jones | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jeff Otah | OT | 1 | 1 | 0.0 | 0 | 0 | 0 |