Franchise 77 seasons 563–571–9 all-time 20 playoff trips 1 Super Bowls
1999 players
Passing
| Shane Matthews | 275 | 167 | 1,645 | 10 | 6 | 6.0 |
| Cade McNown | 235 | 127 | 1,465 | 8 | 10 | 6.2 |
| Jim Miller | 174 | 110 | 1,242 | 7 | 6 | 7.1 |
| Jim Miller | 174 | 110 | 1,242 | 7 | 6 | 7.1 |
Rushing
| Curtis Enis | 287 | 916 | 3 | 3.2 |
| Cade McNown | 32 | 160 | 0 | 5.0 |
| James Allen | 32 | 119 | 0 | 3.7 |
| Glyn Milburn | 16 | 102 | 1 | 6.4 |
| Shane Matthews | 14 | 31 | 0 | 2.2 |
| Edgar Bennett | 6 | 28 | 0 | 4.7 |
| Bobby Engram | 2 | 11 | 0 | 5.5 |
| Jim Miller | 3 | 9 | 0 | 3.0 |
| Jim Miller | 3 | 9 | 0 | 3.0 |
| Marty Booker | 1 | 8 | 0 | 8.0 |
| Macey Brooks | 1 | 7 | 0 | 7.0 |
| Curtis Conway | 1 | -2 | 0 | -2.0 |
| Todd Sauerbrun | 1 | -2 | 0 | -2.0 |
Receiving
| Marcus Robinson | 149 | 84 | 1,400 | 9 | 9.4 |
| Bobby Engram | 147 | 88 | 947 | 4 | 6.4 |
| Curtis Conway | 79 | 44 | 426 | 4 | 5.4 |
| Curtis Enis | 68 | 45 | 340 | 2 | 5.0 |
| Ryan Wetnight | 60 | 38 | 277 | 1 | 4.6 |
| Marty Booker | 34 | 19 | 219 | 3 | 6.4 |
| Macey Brooks | 27 | 14 | 160 | 0 | 5.9 |
| Glyn Milburn | 30 | 20 | 151 | 0 | 5.0 |
| Edgar Bennett | 21 | 14 | 116 | 0 | 5.5 |
| John Allred | 17 | 13 | 102 | 1 | 6.0 |
| James Allen | 11 | 9 | 91 | 0 | 8.3 |
| Alonzo Mayes | 15 | 8 | 82 | 1 | 5.5 |
| Ty Hallock | 8 | 6 | 22 | 0 | 2.8 |
| D'Wayne Bates | 7 | 2 | 19 | 0 | 2.7 |
Defense
| Barry Minter | RLB/MLB | 122 | 97 | 3.0 | 2 | 6 | 3 |
| Tony Parrish | SS | 105 | 92 | 0.0 | 1 | 7 | 1 |
| Sean Harris | MLB | 71 | 56 | 0.0 | 1 | 5 | 2 |
| Walt Harris | LCB | 70 | 60 | 1.0 | 1 | 14 | 0 |
| Warrick Holdman | RLB | 68 | 55 | 2.0 | 0 | 0 | 2 |
| Mike Wells | RDT | 68 | 51 | 1.0 | 0 | 4 | 1 |
| Ricardo McDonald | LLB | 65 | 50 | 0.5 | 0 | 1 | 2 |
| Terry Cousin | RCB | 57 | 48 | 0.0 | 2 | 2 | 1 |
| Chris Hudson | FS | 55 | 43 | 1.0 | 3 | 6 | 1 |
| Jim Flanigan | LDT | 43 | 35 | 6.0 | 1 | 3 | 2 |
| Bryan Robinson | LDE | 42 | 38 | 5.0 | 0 | 2 | 0 |
| Van Tuinei | RDE | 38 | 31 | 2.5 | 0 | 0 | 2 |
| Jerry Azumah | DB | 33 | 27 | 0.0 | 0 | 1 | 1 |
| Frankie Smith | DB | 26 | 23 | 1.0 | 0 | 2 | 0 |
| Khari Samuel | LB | 21 | 15 | 0.0 | 0 | 0 | 0 |
| Keith Burns | LB | 18 | 17 | 0.0 | 1 | 1 | 1 |
| Russell Davis | RDE | 17 | 13 | 2.0 | 0 | 2 | 0 |
| Clyde Simmons | DE | 14 | 12 | 7.0 | 0 | 2 | 1 |
| Rosevelt Colvin | LB | 13 | 11 | 2.0 | 0 | 0 | 0 |
| Raymond Austin | DB | 11 | 7 | 0.0 | 0 | 0 | 0 |
| Shane Burton | DT | 11 | 7 | 3.0 | 1 | 3 | 0 |
| Raymond Austin | DB | 11 | 7 | 0.0 | 0 | 0 | 0 |
| Chris Villarrial | G | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Blake Brockermeyer | OT | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Patrick Mannelly | LS | 2 | 1 | 0.0 | 0 | 0 | 0 |
| Todd Perry | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jim Miller | QB | 1 | 0 | 0.0 | 0 | 0 | 0 |
| Olin Kreutz | C | 1 | 1 | 0.0 | 0 | 0 | 0 |
| James O. Williams | OT | 1 | 1 | 0.0 | 0 | 0 | 0 |