Franchise 77 seasons 563–571–9 all-time 20 playoff trips 1 Super Bowls
2001 players
Passing
| Jim Miller | 395 | 228 | 2,299 | 13 | 10 | 5.8 |
| Shane Matthews | 129 | 84 | 694 | 5 | 6 | 5.4 |
| Marty Booker | 2 | 1 | 34 | 1 | 0 | 17.0 |
| Brad Maynard | 1 | 1 | 27 | 1 | 0 | 27.0 |
| Leon Johnson | 1 | 1 | 18 | 0 | 0 | 18.0 |
Rushing
| Anthony Thomas | 278 | 1,183 | 7 | 4.3 |
| James Allen | 135 | 469 | 1 | 3.5 |
| Leon Johnson | 20 | 99 | 4 | 5.0 |
| Marty Booker | 4 | 8 | 0 | 2.0 |
| Shane Matthews | 4 | 5 | 0 | 1.2 |
| Autry Denson | 1 | 4 | 0 | 4.0 |
| Brad Maynard | 1 | -10 | 0 | -10.0 |
| Jim Miller | 29 | -19 | 0 | -0.7 |
Receiving
| Marty Booker | 157 | 100 | 1,071 | 8 | 6.8 |
| Dez White | 82 | 45 | 428 | 0 | 5.2 |
| David Terrell | 63 | 34 | 415 | 4 | 6.6 |
| Marcus Robinson | 42 | 23 | 269 | 2 | 6.4 |
| James Allen | 42 | 30 | 203 | 1 | 4.8 |
| Anthony Thomas | 30 | 22 | 178 | 0 | 5.9 |
| D'Wayne Bates | 14 | 9 | 160 | 1 | 11.4 |
| Fred Baxter | 44 | 22 | 148 | 2 | 3.4 |
| Daimon Shelton | 18 | 12 | 76 | 1 | 4.2 |
| John Davis | 17 | 11 | 68 | 0 | 4.0 |
| Brian Urlacher | 1 | 1 | 27 | 1 | 27.0 |
| Ahmad Merritt | 6 | 2 | 20 | 0 | 3.3 |
| Leon Johnson | 2 | 1 | 0 | 0 | 0.0 |
Defense
| Brian Urlacher | MLB | 111 | 84 | 6.0 | 3 | 8 | 2 |
| Warrick Holdman | LB | 87 | 73 | 1.5 | 1 | 9 | 3 |
| R.W. McQuarters | CB | 72 | 58 | 1.0 | 3 | 15 | 2 |
| Michael Green | DB | 65 | 59 | 3.0 | 0 | 4 | 2 |
| Tony Parrish | S | 61 | 50 | 1.0 | 3 | 4 | 0 |
| Mike Brown | S | 60 | 48 | 3.0 | 5 | 11 | 2 |
| Rosevelt Colvin | LB | 60 | 50 | 10.5 | 2 | 8 | 3 |
| Jerry Azumah | CB | 50 | 43 | 2.0 | 1 | 5 | 1 |
| Phillip Daniels | DE | 47 | 40 | 9.0 | 0 | 10 | 3 |
| Walt Harris | CB | 45 | 43 | 0.0 | 1 | 10 | 1 |
| Bryan Robinson | NT | 44 | 34 | 4.5 | 0 | 7 | 2 |
| Keith Traylor | NT | 30 | 26 | 2.0 | 1 | 2 | 1 |
| Ted Washington | NT | 29 | 21 | 1.5 | 0 | 4 | 0 |
| Greg Jones | LB | 17 | 17 | 0.0 | 0 | 0 | 1 |
| Larry Whigham | DB | 15 | 12 | 0.0 | 0 | 0 | 0 |
| Leon Johnson | RB | 10 | 8 | 0.0 | 0 | 0 | 0 |
| Robert Newkirk | DT | 9 | 7 | 1.0 | 0 | 0 | 1 |
| Patrick Mannelly | LS | 9 | 7 | 0.0 | 0 | 0 | 0 |
| Carl Powell | DE | 9 | 8 | 0.0 | 0 | 1 | 0 |
| Bobbie Howard | OLB | 8 | 4 | 0.0 | 0 | 1 | 0 |
| Than Merrill | DB | 7 | 7 | 0.0 | 0 | 0 | 0 |
| Autry Denson | RB | 7 | 7 | 0.0 | 0 | 0 | 0 |
| Alfonso Boone | DE | 6 | 4 | 2.0 | 0 | 1 | 0 |
| Todd McMillon | DB | 4 | 4 | 0.0 | 0 | 0 | 0 |
| Dustin Lyman | TE | 3 | 3 | 0.0 | 0 | 0 | 0 |
| David Terrell | WR | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Anthony Thomas | RB | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Paul Edinger | K | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Marcus Robinson | WR | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Reggie Austin | CB | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Daimon Shelton | FB | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Brad Maynard | P | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Fred Baxter | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Scott Dragos | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| John Davis | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Marty Booker | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jim Miller | QB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Ahmad Merritt | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Dez White | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Karon Riley | LB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Joe Tafoya | DE | 1 | 1 | 0.0 | 0 | 0 | 0 |