Franchise 77 seasons 563–571–9 all-time 20 playoff trips 1 Super Bowls
2004 players
Passing
| Chad Hutchinson | 161 | 92 | 903 | 4 | 3 | 5.6 |
| Craig Krenzel | 127 | 59 | 718 | 3 | 6 | 5.7 |
| Rex Grossman | 84 | 47 | 607 | 1 | 3 | 7.2 |
| Jonathan Quinn | 98 | 51 | 413 | 1 | 3 | 4.2 |
| Paul Edinger | 1 | 0 | 0 | 0 | 1 | 0.0 |
Rushing
| Thomas Jones | 240 | 948 | 7 | 4.0 |
| Anthony Thomas | 122 | 404 | 2 | 3.3 |
| Bobby Wade | 12 | 76 | 0 | 6.3 |
| Rex Grossman | 11 | 48 | 1 | 4.4 |
| Craig Krenzel | 18 | 41 | 0 | 2.3 |
| Jonathan Quinn | 3 | 35 | 0 | 11.7 |
| Bernard Berrian | 8 | 28 | 0 | 3.5 |
| Adrian Peterson | 6 | 19 | 0 | 3.2 |
| Chad Hutchinson | 6 | 14 | 0 | 2.3 |
| David Terrell | 3 | 10 | 0 | 3.3 |
| Jason McKie | 1 | 1 | 0 | 1.0 |
Receiving
| David Terrell | 42 | 699 | 1 | 16.6 |
| Bobby Wade | 42 | 481 | 0 | 11.5 |
| Thomas Jones | 56 | 427 | 0 | 7.6 |
| Desmond Clark | 24 | 282 | 1 | 11.8 |
| Bernard Berrian | 15 | 225 | 2 | 15.0 |
| Justin Gage | 12 | 156 | 0 | 13.0 |
| Anthony Thomas | 17 | 132 | 0 | 7.8 |
| Dustin Lyman | 11 | 73 | 1 | 6.6 |
| Jason McKie | 13 | 70 | 2 | 5.4 |
| Bryan Johnson | 14 | 55 | 2 | 3.9 |
| Adrian Peterson | 2 | 30 | 0 | 15.0 |
| John Gilmore | 1 | 11 | 0 | 11.0 |
Defense
| Lance Briggs | OLB | 109 | 86 | 0.0 | 1 | 10 | 0 |
| Michael Green | DB | 93 | 70 | 1.0 | 2 | 9 | 2 |
| Hunter Hillenmeyer | MLB | 66 | 47 | 2.0 | 0 | 2 | 1 |
| Todd Johnson | DB | 62 | 50 | 0.0 | 0 | 2 | 0 |
| R.W. McQuarters | CB | 58 | 46 | 0.0 | 2 | 9 | 0 |
| Brian Urlacher | MLB | 55 | 38 | 4.0 | 1 | 7 | 2 |
| Jerry Azumah | CB | 48 | 37 | 1.0 | 4 | 9 | 2 |
| Alex Brown | DE | 38 | 28 | 7.0 | 0 | 9 | 3 |
| Charles Tillman | CB | 38 | 31 | 0.0 | 0 | 5 | 1 |
| Adewale Ogunleye | DE | 36 | 29 | 6.0 | 0 | 2 | 1 |
| Ian Scott | NT | 36 | 26 | 2.0 | 0 | 3 | 0 |
| Tommie Harris | DT | 33 | 19 | 2.0 | 0 | 2 | 1 |
| Michael Haynes | DE | 27 | 21 | 2.0 | 1 | 3 | 0 |
| Nathan Vasher | CB | 26 | 25 | 0.0 | 5 | 9 | 0 |
| Joe Odom | LB | 20 | 14 | 0.0 | 0 | 0 | 0 |
| Adrian Peterson | RB | 18 | 13 | 0.0 | 0 | 0 | 2 |
| Bobby Gray | S | 18 | 12 | 0.0 | 1 | 1 | 0 |
| Todd McMillon | DB | 15 | 11 | 0.0 | 0 | 1 | 0 |
| Cameron Worrell | DB | 14 | 14 | 0.0 | 0 | 0 | 1 |
| Israel Idonije | DE | 12 | 9 | 1.0 | 0 | 1 | 0 |
| John Gilmore | TE | 10 | 9 | 0.0 | 0 | 0 | 0 |
| Alfonso Boone | DE | 10 | 8 | 3.0 | 0 | 1 | 0 |
| Tank Johnson | DT | 9 | 7 | 1.0 | 0 | 0 | 0 |
| Marcus Reese | LB | 7 | 4 | 0.0 | 0 | 0 | 1 |
| Dustin Lyman | TE | 6 | 4 | 0.0 | 0 | 0 | 0 |
| Alfonso Marshall | CB | 6 | 3 | 0.0 | 0 | 0 | 0 |
| Patrick Mannelly | LS | 5 | 4 | 0.0 | 0 | 0 | 0 |
| Mike Brown | S | 5 | 4 | 0.0 | 0 | 1 | 0 |
| Jerrell Pippens | DB | 4 | 4 | 0.0 | 0 | 0 | 0 |
| Jason McKie | RB | 4 | 3 | 0.0 | 0 | 0 | 0 |
| Bryan Johnson | FB | 4 | 3 | 0.0 | 0 | 0 | 0 |
| Olin Kreutz | C | 4 | 4 | 0.0 | 0 | 0 | 0 |
| John Tait | OT | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Desmond Clark | TE | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Qasim Mitchell | OT | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Shurron Pierson | DE | 2 | 1 | 0.0 | 0 | 0 | 0 |
| Paul Edinger | K | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Brad Maynard | P | 2 | 1 | 0.0 | 0 | 0 | 0 |
| Jeremy Cain | LS | 2 | 0 | 0.0 | 0 | 0 | 0 |
| Anthony Thomas | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Steve Edwards | OT | 1 | 1 | 0.0 | 0 | 0 | 0 |
| John Owens | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Daryl Jones | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Marc Colombo | OT | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Terrence Metcalf | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Bobby Wade | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jason Shivers | SAF | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Alain Kashama | DE | 1 | 0 | 0.0 | 0 | 0 | 0 |
| Bernard Berrian | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Craig Krenzel | QB | 1 | 1 | 0.0 | 0 | 0 | 0 |