Franchise 74 seasons 523–560–11 all-time 26 playoff trips 0 Super Bowls
2007 players
Passing
| Derek Anderson | 527 | 298 | 3,786 | 29 | 19 | 7.2 |
| Brady Quinn | 8 | 3 | 45 | 0 | 0 | 5.6 |
| Charlie Frye | 10 | 4 | 34 | 0 | 1 | 3.4 |
Rushing
| Jamal Lewis | 299 | 1,303 | 9 | 4.4 |
| Jason Wright | 60 | 277 | 1 | 4.6 |
| Jerome Harrison | 23 | 142 | 0 | 6.2 |
| Derek Anderson | 30 | 77 | 3 | 2.6 |
| Josh Cribbs | 9 | 61 | 0 | 6.8 |
| Lawrence Vickers | 15 | 43 | 0 | 2.9 |
| Charlie Frye | 1 | 1 | 0 | 1.0 |
| Dave Zastudil | 2 | -3 | 0 | -1.5 |
Receiving
| Braylon Edwards | 0 | 80 | 1,289 | 16 | 1289.0 |
| Kellen Winslow | 0 | 82 | 1,106 | 5 | 1106.0 |
| Joe Jurevicius | 0 | 50 | 614 | 3 | 614.0 |
| Jamal Lewis | 0 | 30 | 248 | 2 | 248.0 |
| Jason Wright | 1 | 24 | 232 | 0 | 232.0 |
| Tim Carter | 0 | 8 | 117 | 1 | 117.0 |
| Steve Heiden | 0 | 12 | 104 | 0 | 104.0 |
| Lawrence Vickers | 0 | 13 | 91 | 2 | 91.0 |
| Josh Cribbs | 0 | 3 | 37 | 0 | 37.0 |
| Jerome Harrison | 0 | 2 | 19 | 0 | 19.0 |
| Darnell Dinkins | 0 | 1 | 8 | 0 | 8.0 |
Defense
| D'Qwell Jackson | ILB | 82 | 56 | 1.0 | 1 | 3 | 0 |
| Sean Jones | S | 82 | 55 | 0.5 | 5 | 10 | 1 |
| Leigh Bodden | DB | 80 | 68 | 0.0 | 6 | 15 | 0 |
| Leon Williams | LB | 70 | 48 | 4.0 | 0 | 3 | 0 |
| Eric Wright | DB | 63 | 58 | 1.0 | 1 | 11 | 0 |
| Andra Davis | ILB | 52 | 36 | 0.0 | 0 | 4 | 1 |
| Brodney Pool | S | 50 | 38 | 0.5 | 2 | 6 | 0 |
| Shaun Smith | DT | 47 | 33 | 2.0 | 0 | 3 | 1 |
| Robaire Smith | DE | 43 | 29 | 4.0 | 0 | 2 | 0 |
| Daven Holly | DB | 41 | 38 | 0.0 | 0 | 8 | 1 |
| Kamerion Wimbley | OLB | 39 | 27 | 4.0 | 0 | 1 | 3 |
| Orpheus Roye | DE | 29 | 16 | 0.5 | 0 | 0 | 0 |
| Willie McGinest | OLB | 27 | 16 | 2.5 | 0 | 5 | 0 |
| Mike Adams | FS | 24 | 22 | 1.0 | 0 | 1 | 0 |
| Brandon McDonald | DB | 22 | 17 | 0.0 | 2 | 10 | 0 |
| Josh Cribbs | WR | 19 | 16 | 0.0 | 0 | 0 | 0 |
| Ethan Kelley | NT | 19 | 10 | 1.0 | 0 | 0 | 1 |
| Chaun Thompson | LB | 19 | 13 | 1.0 | 0 | 1 | 0 |
| Antwan Peek | OLB | 18 | 11 | 4.0 | 0 | 4 | 1 |
| Kris Griffin | LB | 11 | 9 | 0.0 | 0 | 0 | 0 |
| Nick Sorensen | DB | 11 | 9 | 0.0 | 0 | 0 | 1 |
| Simon Fraser | DE | 9 | 6 | 0.0 | 0 | 1 | 0 |
| Darnell Dinkins | TE | 7 | 5 | 0.0 | 0 | 0 | 1 |
| Braylon Edwards | WR | 6 | 6 | 0.0 | 0 | 0 | 0 |
| Jason Wright | RB | 6 | 6 | 0.0 | 0 | 0 | 0 |
| Kenny Wright | DB | 5 | 5 | 0.0 | 0 | 0 | 0 |
| Ted Washington | NT | 5 | 4 | 0.0 | 0 | 0 | 0 |
| Hank Fraley | C | 5 | 5 | 0.0 | 0 | 0 | 0 |
| Ryan Pontbriand | LS | 4 | 4 | 0.0 | 0 | 0 | 0 |
| David McMillan | LB | 4 | 3 | 0.0 | 0 | 0 | 0 |
| Lawrence Vickers | FB | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Kellen Winslow | TE | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Kevin Shaffer | OT | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Joe Jurevicius | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jamal Lewis | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Ryan Tucker | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Bobby Hamilton | DE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Keith Adams | LB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Colby Bockwoldt | LB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Eric Steinbach | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Derek Anderson | QB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Joe Thomas | OT | 1 | 1 | 0.0 | 0 | 0 | 0 |