Franchise 57 seasons 499–381–6 all-time 24 playoff trips 3 Super Bowls
2002 players
Passing
| Brian Griese | 436 | 291 | 3,214 | 15 | 15 | 7.4 |
| Steve Beuerlein | 117 | 68 | 925 | 6 | 5 | 7.9 |
| Rod Smith | 1 | 0 | 0 | 0 | 0 | 0.0 |
Rushing
| Clinton Portis | 273 | 1,508 | 15 | 5.5 |
| Mike Anderson | 84 | 386 | 2 | 4.6 |
| Olandis Gary | 37 | 147 | 1 | 4.0 |
| Brian Griese | 37 | 107 | 1 | 2.9 |
| Ashley Lelie | 4 | 40 | 0 | 10.0 |
| Scottie Montgomery | 4 | 27 | 0 | 6.8 |
| Ed McCaffrey | 2 | 22 | 0 | 11.0 |
| Reuben Droughns | 4 | 11 | 1 | 2.8 |
| Steve Beuerlein | 5 | 9 | 1 | 1.8 |
| Rod Smith | 6 | 9 | 0 | 1.5 |
| Micah Knorr | 1 | -10 | 0 | -10.0 |
Receiving
| Rod Smith | 147 | 89 | 1,027 | 5 | 7.0 |
| Ed McCaffrey | 103 | 69 | 903 | 2 | 8.8 |
| Shannon Sharpe | 88 | 61 | 686 | 3 | 7.8 |
| Ashley Lelie | 53 | 35 | 525 | 2 | 9.9 |
| Clinton Portis | 48 | 33 | 364 | 2 | 7.6 |
| Dwayne Carswell | 29 | 21 | 189 | 1 | 6.5 |
| Mike Anderson | 24 | 18 | 167 | 2 | 7.0 |
| Olandis Gary | 20 | 18 | 148 | 0 | 7.4 |
| Reuben Droughns | 7 | 5 | 53 | 1 | 7.6 |
| Scottie Montgomery | 6 | 4 | 51 | 1 | 8.5 |
| Patrick Hape | 14 | 6 | 26 | 2 | 1.9 |
Defense
| Al Wilson | MLB | 112 | 80 | 5.0 | 0 | 4 | 1 |
| John Mobley | OLB | 84 | 57 | 1.0 | 0 | 3 | 1 |
| Ian Gold | OLB | 80 | 65 | 6.5 | 0 | 4 | 1 |
| Deltha O'Neal | CB | 63 | 53 | 0.0 | 5 | 9 | 0 |
| Kenoy Kennedy | S | 62 | 48 | 0.0 | 0 | 6 | 0 |
| Denard Walker | CB | 58 | 50 | 0.0 | 1 | 10 | 0 |
| Tyrone Poole | DB | 49 | 39 | 1.0 | 0 | 10 | 1 |
| Izell Reese | FS | 43 | 31 | 0.5 | 0 | 4 | 1 |
| Trevor Pryce | DE | 41 | 35 | 9.0 | 0 | 1 | 1 |
| Kavika Pittman | DE | 31 | 22 | 0.0 | 0 | 1 | 1 |
| Chester McGlockton | DT | 31 | 26 | 2.5 | 0 | 3 | 0 |
| Sam Brandon | DB | 25 | 20 | 0.0 | 0 | 1 | 1 |
| Lional Dalton | DT | 25 | 20 | 1.0 | 0 | 2 | 1 |
| Montae Reagor | DE | 18 | 10 | 1.0 | 1 | 1 | 1 |
| Bertrand Berry | OLB | 17 | 13 | 6.5 | 0 | 1 | 0 |
| Monsanto Pope | DT | 17 | 14 | 4.0 | 0 | 1 | 0 |
| Willie Middlebrooks | DB | 15 | 13 | 0.0 | 0 | 0 | 0 |
| Reuben Droughns | RB | 13 | 11 | 0.0 | 0 | 0 | 1 |
| Keith Burns | LB | 11 | 8 | 0.0 | 0 | 0 | 1 |
| Donnie Spragan | OLB | 11 | 9 | 0.0 | 0 | 0 | 1 |
| Reggie Hayward | DE | 9 | 6 | 0.0 | 0 | 0 | 0 |
| Kelly Herndon | DB | 8 | 5 | 0.0 | 1 | 1 | 0 |
| Keith Washington | DE | 8 | 8 | 0.0 | 1 | 1 | 0 |
| Rod Smith | WR | 6 | 6 | 0.0 | 0 | 0 | 0 |
| Scottie Montgomery | WR | 6 | 4 | 0.0 | 0 | 0 | 0 |
| Lenny Walls | CB | 6 | 5 | 0.0 | 0 | 0 | 1 |
| Ed McCaffrey | WR | 5 | 5 | 0.0 | 0 | 0 | 0 |
| Micah Knorr | P | 4 | 4 | 0.0 | 0 | 0 | 0 |
| Jimmy Spencer | DB | 4 | 4 | 0.0 | 0 | 0 | 0 |
| Mike Leach | LS | 2 | 1 | 0.0 | 0 | 0 | 0 |
| Matt Lepsis | OT | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Olandis Gary | RB | 2 | 1 | 0.0 | 0 | 0 | 0 |
| Ben Hamilton | G | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Tom Nalen | C | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Patrick Hape | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Brian Griese | QB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jason Elam | K | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Ephraim Salaam | OT | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Dan Neil | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Mike Anderson | RB | 1 | 1 | 0.0 | 0 | 1 | 0 |
| Steve Herndon | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Herb Haygood | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Clinton Portis | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |