Franchise 57 seasons 499–381–6 all-time 24 playoff trips 3 Super Bowls
2006 players
Passing
| Jake Plummer | 317 | 175 | 1,994 | 11 | 13 | 6.3 |
| Jay Cutler | 137 | 81 | 1,001 | 9 | 5 | 7.3 |
Rushing
| Tatum Bell | 233 | 1,025 | 2 | 4.4 |
| Mike Bell | 157 | 677 | 8 | 4.3 |
| Javon Walker | 9 | 123 | 1 | 13.7 |
| Jake Plummer | 36 | 112 | 1 | 3.1 |
| Cecil Sapp | 10 | 80 | 0 | 8.0 |
| Damien Nash | 18 | 66 | 0 | 3.7 |
| Kyle Johnson | 5 | 30 | 0 | 6.0 |
| Jay Cutler | 12 | 18 | 0 | 1.5 |
| Brandon Marshall | 2 | 12 | 0 | 6.0 |
| Cedric Cobbs | 3 | 9 | 0 | 3.0 |
| Tony Scheffler | 1 | 3 | 0 | 3.0 |
| Jason Elam | 1 | 2 | 0 | 2.0 |
| Rod Smith | 1 | -5 | 0 | -5.0 |
Receiving
| Javon Walker | 69 | 1,084 | 8 | 15.7 |
| Rod Smith | 52 | 512 | 3 | 9.8 |
| Brandon Marshall | 20 | 309 | 2 | 15.4 |
| Tony Scheffler | 18 | 286 | 4 | 15.9 |
| David Kircus | 9 | 187 | 0 | 20.8 |
| Stephen Alexander | 18 | 160 | 2 | 8.9 |
| Mike Bell | 20 | 158 | 0 | 7.9 |
| Tatum Bell | 24 | 115 | 0 | 4.8 |
| Nate Jackson | 5 | 49 | 0 | 9.8 |
| Damien Nash | 4 | 41 | 0 | 10.2 |
| Kyle Johnson | 7 | 37 | 1 | 5.3 |
| Cecil Sapp | 8 | 34 | 0 | 4.2 |
| Chad Mustard | 2 | 23 | 0 | 11.5 |
Defense
| Al Wilson | MLB | 86 | 63 | 1.0 | 0 | 4 | 1 |
| Champ Bailey | CB | 80 | 68 | 1.0 | 10 | 21 | 0 |
| Darrent Williams | CB | 80 | 69 | 1.0 | 4 | 9 | 1 |
| Ian Gold | OLB | 76 | 55 | 0.0 | 0 | 4 | 1 |
| John Lynch | FS | 76 | 51 | 0.0 | 0 | 5 | 2 |
| D.J. Williams | MLB | 62 | 45 | 1.0 | 0 | 2 | 1 |
| Domonique Foxworth | DB | 53 | 40 | 0.0 | 1 | 6 | 1 |
| Ebenezer Ekuban | DE | 51 | 36 | 7.0 | 0 | 0 | 1 |
| Michael Myers | DT | 47 | 27 | 2.0 | 0 | 2 | 1 |
| Nick Ferguson | FS | 34 | 26 | 0.0 | 1 | 4 | 1 |
| Kenard Lang | DE | 28 | 20 | 7.0 | 0 | 1 | 1 |
| Curome Cox | DB | 25 | 19 | 0.0 | 1 | 5 | 0 |
| John Engelberger | DE | 24 | 17 | 1.0 | 0 | 4 | 2 |
| Patrick Chukwurah | LB | 24 | 17 | 4.5 | 0 | 1 | 1 |
| Karl Paymah | DB | 24 | 21 | 0.0 | 0 | 2 | 0 |
| Gerard Warren | DT | 22 | 15 | 2.0 | 0 | 3 | 0 |
| Demetrin Veal | DE | 21 | 10 | 2.0 | 0 | 2 | 1 |
| Elvis Dumervil | DE | 16 | 12 | 7.5 | 0 | 1 | 1 |
| Hamza Abdullah | DB | 12 | 9 | 0.0 | 0 | 0 | 1 |
| Sam Brandon | DB | 11 | 8 | 0.0 | 0 | 1 | 1 |
| Keith Burns | LB | 10 | 9 | 0.0 | 0 | 0 | 1 |
| Nate Webster | MLB | 9 | 6 | 0.0 | 0 | 0 | 0 |
| Cecil Sapp | RB | 7 | 5 | 0.0 | 0 | 0 | 0 |
| Brandon Marshall | WR | 6 | 6 | 0.0 | 0 | 0 | 1 |
| Louis Green | LB | 6 | 4 | 0.0 | 0 | 0 | 1 |
| Nate Jackson | TE | 5 | 4 | 0.0 | 0 | 0 | 0 |
| Kyle Johnson | RB | 5 | 4 | 0.0 | 0 | 0 | 1 |
| Mike Leach | LS | 4 | 3 | 0.0 | 0 | 0 | 0 |
| Quentin Harris | DB | 4 | 3 | 0.0 | 0 | 0 | 0 |
| Steve Cargile | DB | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Paul Ernster | P | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Rod Smith | WR | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Jake Plummer | QB | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Erik Pears | OT | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Ben Hamilton | G | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Tony Scheffler | TE | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Stephen Alexander | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Tom Nalen | C | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Todd Devoe | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Cooper Carlisle | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Javon Walker | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Tatum Bell | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Kenny Peterson | DE | 1 | 0 | 0.0 | 0 | 0 | 0 |
| George Foster | OT | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jay Cutler | QB | 1 | 1 | 0.0 | 0 | 0 | 0 |