Franchise 57 seasons 499–381–6 all-time 24 playoff trips 3 Super Bowls
2012 players
Passing
| Peyton Manning | 583 | 400 | 4,659 | 37 | 11 | 8.0 |
| Brock Osweiler | 4 | 2 | 12 | 0 | 0 | 3.0 |
| Matt Prater | 1 | 0 | 0 | 0 | 0 | 0.0 |
Rushing
| Willis McGahee | 167 | 731 | 4 | 4.4 |
| Knowshon Moreno | 138 | 525 | 4 | 3.8 |
| Ronnie Hillman | 85 | 330 | 1 | 3.9 |
| Lance Ball | 42 | 158 | 1 | 3.8 |
| Jacob Hester | 17 | 81 | 2 | 4.8 |
| Andre Caldwell | 1 | 14 | 0 | 14.0 |
| Peyton Manning | 23 | 6 | 0 | 0.3 |
| Brock Osweiler | 8 | -13 | 0 | -1.6 |
Receiving
| Demaryius Thomas | 141 | 94 | 1,434 | 10 | 10.2 |
| Eric Decker | 122 | 85 | 1,064 | 13 | 8.7 |
| Jacob Tamme | 84 | 52 | 555 | 2 | 6.6 |
| Brandon Stokley | 59 | 45 | 544 | 5 | 9.2 |
| Joel Dreessen | 58 | 41 | 356 | 5 | 6.1 |
| Willis McGahee | 33 | 26 | 221 | 0 | 6.7 |
| Knowshon Moreno | 26 | 21 | 167 | 0 | 6.4 |
| Matt Willis | 22 | 10 | 90 | 0 | 4.1 |
| Virgil Green | 6 | 5 | 63 | 0 | 10.5 |
| Ronnie Hillman | 12 | 10 | 62 | 0 | 5.2 |
| Lance Ball | 11 | 7 | 61 | 1 | 5.5 |
| Andre Caldwell | 4 | 1 | 18 | 0 | 4.5 |
| Trindon Holliday | 2 | 2 | 17 | 0 | 8.5 |
| Chris Gronkowski | 1 | 1 | 11 | 0 | 11.0 |
| Jacob Hester | 1 | 1 | 7 | 0 | 7.0 |
| Mitch Unrein | 1 | 1 | 1 | 1 | 1.0 |
Defense
| Wesley Woodyard | ILB | 114 | 70 | 5.5 | 3 | 6 | 1 |
| Mike Adams | FS | 78 | 59 | 1.0 | 0 | 11 | 2 |
| Rahim Moore | FS | 71 | 59 | 1.0 | 1 | 6 | 0 |
| Von Miller | OLB | 67 | 54 | 18.5 | 1 | 2 | 6 |
| Champ Bailey | CB | 65 | 60 | 0.0 | 2 | 8 | 0 |
| Chris Harris | CB | 59 | 49 | 2.5 | 3 | 9 | 0 |
| Elvis Dumervil | DE | 52 | 30 | 11.0 | 0 | 1 | 6 |
| Keith Brooking | MLB | 48 | 28 | 1.0 | 0 | 0 | 1 |
| Derek Wolfe | DE | 38 | 24 | 6.0 | 0 | 2 | 0 |
| Kevin Vickerson | DT | 38 | 26 | 2.0 | 0 | 1 | 1 |
| Justin Bannan | DT | 38 | 24 | 0.0 | 0 | 4 | 1 |
| Danny Trevathan | ILB | 30 | 19 | 1.0 | 0 | 2 | 0 |
| Tony Carter | DB | 26 | 22 | 0.0 | 2 | 11 | 0 |
| Tracy Porter | CB | 21 | 16 | 0.0 | 1 | 6 | 0 |
| Joe Mays | LB | 20 | 7 | 0.5 | 0 | 0 | 0 |
| Mitch Unrein | DT | 18 | 10 | 0.0 | 0 | 0 | 0 |
| Jim Leonhard | FS | 17 | 12 | 0.0 | 2 | 2 | 0 |
| Robert Ayers | DE | 16 | 8 | 2.0 | 0 | 0 | 0 |
| D.J. Williams | MLB | 14 | 10 | 0.0 | 0 | 1 | 0 |
| Nate Irving | ILB | 13 | 9 | 0.0 | 0 | 1 | 0 |
| Omar Bolden | S | 12 | 11 | 0.0 | 0 | 1 | 0 |
| Steven Johnson | LB | 10 | 9 | 0.0 | 0 | 0 | 1 |
| Matt Willis | WR | 7 | 7 | 0.0 | 0 | 0 | 0 |
| Malik Jackson | DT | 5 | 3 | 0.0 | 0 | 0 | 0 |
| David Bruton | S | 5 | 5 | 0.0 | 1 | 1 | 0 |
| Jacob Tamme | TE | 4 | 4 | 0.0 | 0 | 0 | 0 |
| Matt Prater | K | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Orlando Franklin | OT | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Aaron Brewer | LS | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Eric Decker | WR | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Chris Gronkowski | RB | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Virgil Green | TE | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Chris Kuper | G | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Quinton Carter | S | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Manny Ramirez | G | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Ty Warren | DT | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Willis McGahee | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Joel Dreessen | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Britton Colquitt | P | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Andre Caldwell | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Lance Ball | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Zane Beadles | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Demaryius Thomas | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Sealver Siliga | DT | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Duke Ihenacho | FS | 1 | 0 | 0.0 | 0 | 0 | 0 |