Franchise 57 seasons 499–381–6 all-time 24 playoff trips 3 Super Bowls
2015 players
Passing
| Peyton Manning | 331 | 198 | 2,249 | 9 | 17 | 6.8 |
| Brock Osweiler | 275 | 170 | 1,967 | 10 | 6 | 7.2 |
Rushing
| Ronnie Hillman | 207 | 863 | 7 | 4.2 |
| C.J. Anderson | 152 | 720 | 5 | 4.7 |
| Brock Osweiler | 21 | 61 | 1 | 2.9 |
| Juwan Thompson | 18 | 48 | 0 | 2.7 |
| Emmanuel Sanders | 3 | 29 | 0 | 9.7 |
| Andre Caldwell | 1 | 3 | 0 | 3.0 |
| Cody Latimer | 2 | 1 | 0 | 0.5 |
| Trevor Siemian | 1 | -1 | 0 | -1.0 |
| Peyton Manning | 6 | -6 | 0 | -1.0 |
Receiving
| Demaryius Thomas | 177 | 105 | 1,304 | 6 | 7.4 |
| Emmanuel Sanders | 137 | 76 | 1,135 | 6 | 8.3 |
| Owen Daniels | 77 | 46 | 517 | 3 | 6.7 |
| Vernon Davis | 58 | 38 | 395 | 0 | 6.8 |
| Jordan Norwood | 32 | 22 | 207 | 0 | 6.5 |
| Bennie Fowler | 25 | 16 | 203 | 0 | 8.1 |
| C.J. Anderson | 36 | 25 | 183 | 0 | 5.1 |
| Virgil Green | 15 | 12 | 173 | 1 | 11.5 |
| Ronnie Hillman | 35 | 24 | 111 | 0 | 3.2 |
| Andre Caldwell | 22 | 10 | 72 | 2 | 3.3 |
| Cody Latimer | 11 | 6 | 59 | 1 | 5.4 |
| Juwan Thompson | 9 | 6 | 51 | 0 | 5.7 |
Defense
| Danny Trevathan | ILB | 106 | 70 | 0.0 | 2 | 6 | 0 |
| Brandon Marshall | ILB | 96 | 71 | 1.5 | 1 | 4 | 2 |
| Darian Stewart | S | 63 | 48 | 0.0 | 1 | 10 | 1 |
| T.J. Ward | DB | 60 | 49 | 2.0 | 0 | 6 | 2 |
| Chris Harris | CB | 57 | 48 | 0.0 | 2 | 6 | 2 |
| Derek Wolfe | DE | 47 | 33 | 5.5 | 0 | 1 | 0 |
| Shaquil Barrett | LB | 47 | 32 | 5.5 | 0 | 4 | 4 |
| David Bruton | S | 45 | 33 | 1.0 | 2 | 7 | 2 |
| Aqib Talib | CB | 44 | 38 | 0.0 | 3 | 13 | 0 |
| Malik Jackson | DT | 42 | 31 | 5.0 | 0 | 7 | 0 |
| Bradley Roby | CB | 38 | 32 | 0.0 | 1 | 10 | 1 |
| Von Miller | OLB | 35 | 30 | 11.0 | 0 | 1 | 4 |
| Vance Walker | DE | 33 | 23 | 2.0 | 0 | 0 | 0 |
| Sylvester Williams | DT | 25 | 18 | 3.0 | 0 | 0 | 0 |
| DeMarcus Ware | OLB | 25 | 17 | 7.5 | 0 | 0 | 1 |
| Todd Davis | ILB | 21 | 15 | 0.0 | 0 | 0 | 0 |
| Shane Ray | LB | 20 | 15 | 4.0 | 0 | 1 | 0 |
| Corey Nelson | ILB | 16 | 13 | 1.0 | 0 | 0 | 0 |
| Lerentee McCray | DE | 14 | 8 | 0.5 | 0 | 0 | 0 |
| Josh Bush | FS | 13 | 13 | 0.0 | 1 | 1 | 1 |
| Kayvon Webster | S | 11 | 10 | 0.0 | 0 | 2 | 0 |
| Antonio Smith | DE | 9 | 7 | 2.5 | 0 | 2 | 0 |
| Virgil Green | TE | 6 | 6 | 0.0 | 0 | 0 | 0 |
| Darius Kilgo | NT | 6 | 5 | 0.0 | 0 | 1 | 0 |
| Omar Bolden | S | 5 | 3 | 0.0 | 0 | 0 | 0 |
| Bennie Fowler | WR | 5 | 4 | 0.0 | 0 | 0 | 1 |
| C.J. Anderson | RB | 5 | 5 | 0.0 | 0 | 0 | 0 |
| Shiloh Keo | DB | 5 | 5 | 0.0 | 1 | 1 | 0 |
| Cody Latimer | WR | 5 | 4 | 0.0 | 0 | 0 | 0 |
| Emmanuel Sanders | WR | 4 | 4 | 0.0 | 0 | 0 | 0 |
| Ryan Harris | OT | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Max Garcia | G | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Demaryius Thomas | WR | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Owen Daniels | TE | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Andre Caldwell | WR | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Jordan Norwood | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Brandon McManus | K | 1 | 0 | 0.0 | 0 | 0 | 0 |
| Kenny Anunike | DE | 1 | 0 | 0.0 | 0 | 0 | 0 |
| Juwan Thompson | RB | 1 | 0 | 0.0 | 0 | 0 | 0 |
| Matt Paradis | C | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Kapri Bibbs | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Michael Schofield | G | 1 | 1 | 0.0 | 0 | 0 | 1 |
| Lorenzo Doss | CB | 1 | 1 | 0.0 | 0 | 0 | 0 |