Franchise 77 seasons 510–610–21 all-time 18 playoff trips 0 Super Bowls
2010 players
Passing
| Shaun Hill | 416 | 257 | 2,686 | 16 | 12 | 6.5 |
| Drew Stanton | 119 | 69 | 780 | 4 | 3 | 6.6 |
| Matthew Stafford | 96 | 57 | 535 | 6 | 1 | 5.6 |
| Stefan Logan | 1 | 0 | 0 | 0 | 0 | 0.0 |
| Jahvid Best | 1 | 0 | 0 | 0 | 0 | 0.0 |
Rushing
| Jahvid Best | 172 | 563 | 4 | 3.3 |
| Maurice Morris | 90 | 336 | 5 | 3.7 |
| Kevin Smith | 33 | 125 | 0 | 3.8 |
| Shaun Hill | 22 | 123 | 0 | 5.6 |
| Drew Stanton | 18 | 113 | 1 | 6.3 |
| Stefan Logan | 15 | 95 | 0 | 6.3 |
| Nate Burleson | 7 | 81 | 0 | 11.6 |
| Jerome Felton | 22 | 76 | 0 | 3.5 |
| Aaron Brown | 17 | 58 | 0 | 3.4 |
| Calvin Johnson | 4 | 32 | 0 | 8.0 |
| Matthew Stafford | 4 | 11 | 1 | 2.8 |
Receiving
| Calvin Johnson | 137 | 77 | 1,120 | 12 | 8.2 |
| Brandon Pettigrew | 111 | 71 | 722 | 4 | 6.5 |
| Nate Burleson | 86 | 55 | 625 | 6 | 7.3 |
| Jahvid Best | 80 | 58 | 487 | 2 | 6.1 |
| Tony Scheffler | 72 | 45 | 378 | 1 | 5.2 |
| Bryant Johnson | 49 | 18 | 210 | 0 | 4.3 |
| Maurice Morris | 31 | 25 | 170 | 0 | 5.5 |
| Kevin Smith | 16 | 11 | 123 | 0 | 7.7 |
| Jerome Felton | 15 | 8 | 54 | 0 | 3.6 |
| Aaron Brown | 13 | 8 | 45 | 0 | 3.5 |
| Will Heller | 5 | 4 | 37 | 1 | 7.4 |
| Derrick Williams | 5 | 3 | 30 | 0 | 6.0 |
Defense
| Louis Delmas | FS | 80 | 58 | 2.0 | 0 | 1 | 2 |
| Julian Peterson | OLB | 75 | 48 | 1.0 | 0 | 5 | 0 |
| Ndamukong Suh | NT | 62 | 45 | 10.0 | 1 | 3 | 1 |
| Deandre Levy | OLB | 59 | 37 | 0.0 | 2 | 4 | 0 |
| Chris Houston | CB | 52 | 46 | 0.0 | 1 | 12 | 1 |
| Amari Spievey | S | 49 | 35 | 0.0 | 2 | 3 | 0 |
| Ashlee Palmer | OLB | 46 | 36 | 1.0 | 0 | 1 | 3 |
| C.C. Brown | DB | 44 | 35 | 0.0 | 0 | 4 | 1 |
| Kyle Vanden Bosch | DE | 42 | 27 | 4.0 | 0 | 1 | 2 |
| Landon Johnson | MLB | 40 | 32 | 0.0 | 0 | 0 | 2 |
| Bobby Carpenter | LB | 38 | 28 | 0.0 | 0 | 2 | 0 |
| Corey Williams | DT | 33 | 28 | 2.0 | 1 | 4 | 1 |
| Lawrence Jackson | DE | 31 | 18 | 6.0 | 0 | 1 | 1 |
| Alphonso Smith | DB | 31 | 22 | 0.0 | 5 | 8 | 1 |
| Cliff Avril | DE | 30 | 20 | 7.5 | 0 | 5 | 1 |
| John Wendling | FS | 29 | 21 | 0.0 | 0 | 0 | 0 |
| Turk McBride | DE | 29 | 12 | 5.0 | 0 | 0 | 3 |
| Sammie Lee Hill | NT | 27 | 18 | 2.5 | 0 | 0 | 0 |
| Zack Follett | OLB | 20 | 11 | 0.0 | 0 | 1 | 0 |
| Nathan Vasher | CB | 18 | 14 | 0.0 | 1 | 5 | 0 |
| Brandon McDonald | DB | 15 | 12 | 0.0 | 0 | 1 | 0 |
| Eric King | DB | 12 | 8 | 0.0 | 0 | 0 | 0 |
| Isaiah Ekejiuba | LB | 10 | 8 | 0.0 | 0 | 0 | 1 |
| Vinny Ciurciu | LB | 9 | 5 | 0.0 | 0 | 0 | 0 |
| Andre Fluellen | DT | 9 | 7 | 1.0 | 0 | 0 | 0 |
| Spencer Havner | LB | 8 | 5 | 0.0 | 0 | 0 | 0 |
| Prince Miller | DB | 7 | 4 | 0.0 | 0 | 1 | 0 |
| Jerome Felton | FB | 6 | 6 | 0.0 | 0 | 0 | 0 |
| Randy Phillips | DB | 5 | 5 | 0.0 | 0 | 0 | 1 |
| Don Muhlbach | LS | 4 | 2 | 0.0 | 0 | 0 | 0 |
| Nick Harris | P | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Aaron Berry | DB | 3 | 3 | 0.0 | 1 | 1 | 0 |
| Caleb Campbell | DB | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Brian Clark | WR | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Dante Wesley | DB | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Tye Hill | DB | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Tony Scheffler | TE | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Rob Sims | G | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Dave Rayner | K | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Nate Burleson | WR | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Jeff Backus | OT | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Maurice Morris | RB | 2 | 1 | 0.0 | 0 | 0 | 0 |
| Calvin Johnson | WR | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Stephen Peterman | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Will Heller | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Shaun Hill | QB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jason Hanson | K | 1 | 0 | 0.0 | 0 | 0 | 0 |
| Kevin Smith | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Stefan Logan | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Brandon Pettigrew | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jahvid Best | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |