Franchise 77 seasons 510–610–21 all-time 18 playoff trips 0 Super Bowls
2025 players
Passing
| Jared Goff | 578 | 393 | 4,564 | 34 | 8 | 7.9 |
| David Montgomery | 2 | 1 | 3 | 1 | 0 | 1.5 |
| Kyle Allen | 2 | 0 | 0 | 0 | 0 | 0.0 |
Rushing
| Jahmyr Gibbs | 243 | 1,223 | 13 | 5.0 |
| David Montgomery | 158 | 716 | 8 | 4.5 |
| Jared Goff | 19 | 45 | 0 | 2.4 |
| Kalif Raymond | 2 | 19 | 0 | 9.5 |
| Jameson Williams | 6 | 12 | 0 | 2.0 |
| Jacob Saylors | 2 | 11 | 0 | 5.5 |
| Amon-Ra St. Brown | 3 | 9 | 0 | 3.0 |
| Craig Reynolds | 3 | 4 | 0 | 1.3 |
| Sione Vaki | 1 | 4 | 0 | 4.0 |
| Malik Cunningham | 1 | 1 | 0 | 1.0 |
| Grant Stuard | 1 | 0 | 0 | 0.0 |
| Kyle Allen | 3 | -3 | 0 | -1.0 |
Receiving
| Amon-Ra St. Brown | 172 | 117 | 1,401 | 11 | 8.1 |
| Jameson Williams | 102 | 65 | 1,117 | 7 | 11.0 |
| Jahmyr Gibbs | 94 | 77 | 616 | 5 | 6.6 |
| Sam LaPorta | 49 | 40 | 489 | 3 | 10.0 |
| Kalif Raymond | 30 | 24 | 289 | 1 | 9.6 |
| Isaac TeSlaa | 27 | 16 | 239 | 6 | 8.9 |
| David Montgomery | 29 | 24 | 192 | 0 | 6.6 |
| Brock Wright | 22 | 14 | 108 | 2 | 4.9 |
| Anthony Firkser | 10 | 8 | 53 | 0 | 5.3 |
| Tom Kennedy | 4 | 4 | 36 | 0 | 9.0 |
| Shane Zylstra | 5 | 3 | 20 | 0 | 4.0 |
| Ross Dwelley | 5 | 2 | 7 | 0 | 1.4 |
Defense
| Jack Campbell | LB | 174 | 87 | 5.0 | 0 | 4 | 3 |
| Alex Anzalone | MLB | 95 | 52 | 2.5 | 1 | 9 | 0 |
| Derrick Barnes | LB | 78 | 40 | 4.0 | 1 | 3 | 0 |
| Brian Branch | CB | 73 | 46 | 2.5 | 0 | 9 | 1 |
| Aidan Hutchinson | DE | 53 | 35 | 14.5 | 1 | 3 | 4 |
| Amik Robertson | CB | 51 | 42 | 0.0 | 1 | 12 | 2 |
| Rock Ya-Sin | CB | 46 | 26 | 0.0 | 0 | 9 | 0 |
| D.J. Reed | CB | 45 | 36 | 0.0 | 2 | 7 | 1 |
| Thomas Harper | SAF | 37 | 26 | 0.0 | 1 | 5 | 1 |
| Avonte Maddox | FS | 32 | 23 | 0.0 | 1 | 4 | 1 |
| Terrion Arnold | CB | 31 | 23 | 0.0 | 1 | 8 | 0 |
| Roy Lopez | DT | 30 | 11 | 2.0 | 0 | 1 | 0 |
| DJ Reader | DT | 28 | 11 | 0.0 | 0 | 0 | 0 |
| Al-Quadin Muhammad | LB | 25 | 15 | 11.0 | 0 | 0 | 0 |
| Daniel Thomas | SAF | 23 | 10 | 0.0 | 0 | 1 | 0 |
| Trevor Nowaske | LB | 22 | 9 | 1.0 | 0 | 0 | 0 |
| Tyler Lacy | DE | 21 | 6 | 1.0 | 0 | 0 | 0 |
| Kerby Joseph | SAF | 18 | 14 | 0.0 | 3 | 4 | 0 |
| Grant Stuard | LB | 18 | 5 | 0.0 | 0 | 0 | 0 |
| Tyleik Williams | DT | 18 | 8 | 1.0 | 0 | 4 | 0 |
| Tyrus Wheat | LB | 15 | 7 | 1.5 | 0 | 1 | 1 |
| Alim McNeill | DT | 14 | 5 | 1.0 | 0 | 1 | 1 |
| Arthur Maulet | CB | 14 | 11 | 0.0 | 1 | 2 | 0 |
| Marcus Davenport | DE | 13 | 5 | 1.0 | 0 | 0 | 0 |
| Malcolm Rodriguez | LB | 12 | 9 | 0.0 | 0 | 0 | 0 |
| Pat O'Connor | DE | 10 | 5 | 0.0 | 0 | 1 | 0 |
| Jalen Mills | CB | 10 | 3 | 0.0 | 0 | 1 | 0 |
| Sione Vaki | RB | 10 | 6 | 0.0 | 0 | 0 | 0 |
| Jacob Saylors | RB | 8 | 4 | 0.0 | 0 | 0 | 0 |
| Khalil Dorsey | CB | 8 | 6 | 0.0 | 0 | 0 | 0 |
| Zach Cunningham | ILB | 7 | 5 | 0.0 | 0 | 0 | 0 |
| Craig Reynolds | RB | 6 | 4 | 0.0 | 0 | 0 | 0 |
| Nick Whiteside | DB | 5 | 3 | 0.0 | 0 | 3 | 0 |
| Amon-Ra St. Brown | WR | 5 | 4 | 0.0 | 0 | 0 | 0 |
| Jake Bates | K | 4 | 3 | 0.0 | 0 | 0 | 0 |
| Mekhi Wingo | DT | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Loren Strickland | SAF | 2 | 1 | 0.0 | 0 | 0 | 0 |
| Isaac TeSlaa | WR | 2 | 1 | 0.0 | 0 | 0 | 0 |
| Jack Fox | P | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Monty Rice | LB | 2 | 0 | 0.0 | 0 | 0 | 0 |
| Hogan Hatten | LS | 2 | 0 | 0.0 | 0 | 0 | 0 |
| Anthony Pittman | LB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Ty Summers | LB | 1 | 0 | 0.0 | 0 | 0 | 0 |
| Ross Dwelley | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Graham Glasgow | C | 1 | 0 | 0.0 | 0 | 0 | 0 |
| Chris Hubbard | OT | 1 | 0 | 0.0 | 0 | 0 | 0 |
| Shane Zylstra | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jameson Williams | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Sam LaPorta | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |