Franchise 76 seasons 584–547–10 all-time 29 playoff trips 2 Super Bowls
2004 players
Passing
| Peyton Manning | 497 | 336 | 4,557 | 49 | 10 | 9.2 |
| Jim Sorgi | 29 | 17 | 175 | 2 | 0 | 6.0 |
Rushing
| Edgerrin James | 334 | 1,548 | 9 | 4.6 |
| Dominic Rhodes | 53 | 254 | 1 | 4.8 |
| Peyton Manning | 25 | 38 | 0 | 1.5 |
| James Mungro | 5 | 19 | 0 | 3.8 |
| Hunter Smith | 1 | 2 | 0 | 2.0 |
| Reggie Wayne | 1 | -4 | 0 | -4.0 |
| Jim Sorgi | 8 | -5 | 0 | -0.6 |
Receiving
| Reggie Wayne | 77 | 1,210 | 12 | 15.7 |
| Marvin Harrison | 86 | 1,113 | 15 | 12.9 |
| Brandon Stokley | 68 | 1,077 | 10 | 15.8 |
| Edgerrin James | 51 | 483 | 0 | 9.5 |
| Dallas Clark | 25 | 423 | 5 | 16.9 |
| Marcus Pollard | 29 | 309 | 6 | 10.7 |
| James Mungro | 7 | 36 | 3 | 5.1 |
| Ben Hartsock | 4 | 33 | 0 | 8.2 |
| Dominic Rhodes | 2 | 24 | 0 | 12.0 |
| Brad Pyatt | 2 | 12 | 0 | 6.0 |
| Aaron Moorehead | 1 | 7 | 0 | 7.0 |
| Troy Walters | 1 | 5 | 0 | 5.0 |
Defense
| Cato June | LB | 78 | 52 | 0.0 | 2 | 9 | 0 |
| David Thornton | OLB | 74 | 51 | 0.0 | 1 | 1 | 2 |
| Nick Harper | CB | 63 | 44 | 0.0 | 3 | 8 | 0 |
| Rob Morris | LB | 61 | 38 | 3.0 | 1 | 2 | 1 |
| Jim Nelson | LB | 49 | 34 | 0.0 | 1 | 5 | 0 |
| Idrees Bashir | DB | 48 | 31 | 0.0 | 0 | 1 | 1 |
| Jason David | DB | 39 | 35 | 0.0 | 4 | 15 | 1 |
| Raheem Brock | DE | 37 | 26 | 6.0 | 0 | 4 | 1 |
| Von Hutchins | DB | 36 | 23 | 0.0 | 1 | 2 | 0 |
| Montae Reagor | DE | 36 | 28 | 5.0 | 0 | 2 | 1 |
| Mike Doss | DB | 34 | 27 | 1.0 | 2 | 2 | 3 |
| Anthony Floyd | DB | 33 | 20 | 0.0 | 0 | 2 | 0 |
| Gary Brackett | MLB | 32 | 20 | 0.0 | 2 | 3 | 0 |
| Cory Bird | S | 32 | 22 | 0.0 | 0 | 0 | 1 |
| Bob Sanders | S | 31 | 26 | 0.0 | 0 | 1 | 0 |
| Josh Williams | DT | 31 | 24 | 0.0 | 0 | 1 | 1 |
| Robert Mathis | OLB | 30 | 27 | 11.0 | 0 | 0 | 6 |
| Dwight Freeney | DE | 29 | 26 | 16.0 | 0 | 3 | 3 |
| Joseph Jefferson | CB | 26 | 21 | 0.0 | 1 | 3 | 2 |
| Gerome Sapp | DB | 24 | 22 | 0.0 | 0 | 0 | 0 |
| Larry Tripplett | DT | 23 | 20 | 0.0 | 0 | 0 | 1 |
| Donald Strickland | DB | 18 | 13 | 0.0 | 0 | 0 | 0 |
| Gilbert Gardner | LB | 13 | 7 | 0.0 | 0 | 1 | 0 |
| Brad Scioli | DT | 12 | 7 | 2.0 | 0 | 0 | 1 |
| Nick Rogers | LB | 10 | 8 | 0.0 | 0 | 0 | 0 |
| Waine Bacon | DB | 10 | 9 | 0.0 | 1 | 3 | 0 |
| Josh Thomas | DE | 7 | 6 | 1.0 | 0 | 0 | 0 |
| Justin Snow | LS | 5 | 3 | 0.0 | 0 | 0 | 1 |
| Jeff Saturday | C | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Dallas Clark | TE | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Edgerrin James | RB | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Mike Vanderjagt | K | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Brandon Stokley | WR | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Hunter Smith | P | 2 | 0 | 0.0 | 0 | 0 | 0 |
| Keyon Whiteside | LB | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Ben Hartsock | TE | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Jake Scott | G | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Dominic Rhodes | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Reggie Wayne | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Ryan Diem | G | 1 | 0 | 0.0 | 0 | 0 | 0 |
| Tupe Peko | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Brad Pyatt | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Kendyll Pope | LB | 1 | 0 | 0.0 | 0 | 0 | 0 |