Franchise 76 seasons 584–547–10 all-time 29 playoff trips 2 Super Bowls
2006 players
Passing
| Peyton Manning | 557 | 362 | 4,397 | 31 | 9 | 7.9 |
Rushing
| Joseph Addai | 226 | 1,081 | 7 | 4.8 |
| Dominic Rhodes | 187 | 641 | 5 | 3.4 |
| Peyton Manning | 23 | 36 | 4 | 1.6 |
| Ran Carthon | 3 | 4 | 1 | 1.3 |
Receiving
| Marvin Harrison | 95 | 1,366 | 12 | 14.4 |
| Reggie Wayne | 86 | 1,310 | 9 | 15.2 |
| Ben Utecht | 37 | 377 | 0 | 10.2 |
| Dallas Clark | 30 | 367 | 4 | 12.2 |
| Joseph Addai | 40 | 325 | 1 | 8.1 |
| Dominic Rhodes | 36 | 251 | 0 | 7.0 |
| Bryan Fletcher | 18 | 202 | 2 | 11.2 |
| Brandon Stokley | 8 | 85 | 1 | 10.6 |
| Aaron Moorehead | 8 | 82 | 1 | 10.2 |
| Ricky Proehl | 3 | 30 | 0 | 10.0 |
| Dan Klecko | 1 | 2 | 1 | 2.0 |
Defense
| Cato June | LB | 112 | 67 | 0.5 | 3 | 4 | 1 |
| Gary Brackett | MLB | 91 | 55 | 0.5 | 0 | 2 | 3 |
| Antoine Bethea | FS | 75 | 51 | 0.0 | 1 | 5 | 0 |
| Marlin Jackson | DB | 65 | 44 | 0.0 | 1 | 5 | 0 |
| Nick Harper | CB | 61 | 44 | 0.0 | 3 | 9 | 0 |
| Robert Mathis | OLB | 48 | 34 | 9.0 | 0 | 4 | 4 |
| Jason David | DB | 45 | 38 | 0.0 | 2 | 9 | 0 |
| Gilbert Gardner | LB | 43 | 24 | 0.0 | 0 | 4 | 0 |
| Rob Morris | LB | 35 | 23 | 0.0 | 0 | 0 | 0 |
| Raheem Brock | DE | 35 | 22 | 3.5 | 0 | 2 | 3 |
| Anthony McFarland | DT | 30 | 18 | 2.5 | 0 | 0 | 0 |
| Kelvin Hayden | DB | 28 | 21 | 0.0 | 0 | 1 | 0 |
| Dwight Freeney | DE | 23 | 20 | 5.5 | 0 | 2 | 4 |
| Mike Doss | DB | 22 | 17 | 0.0 | 2 | 5 | 0 |
| Bob Sanders | S | 20 | 12 | 0.0 | 1 | 2 | 1 |
| Darrell Reid | DE | 19 | 11 | 0.0 | 0 | 0 | 0 |
| Matt Giordano | FS | 19 | 14 | 0.0 | 1 | 2 | 0 |
| Rocky Boiman | LB | 19 | 14 | 0.0 | 0 | 2 | 1 |
| Bo Schobel | DE | 17 | 11 | 0.5 | 0 | 0 | 0 |
| Freddy Keiaho | LB | 13 | 7 | 0.0 | 0 | 0 | 2 |
| Josh Thomas | DE | 12 | 5 | 1.0 | 0 | 0 | 0 |
| Dexter Reid | DB | 11 | 11 | 0.0 | 0 | 2 | 0 |
| Ryan LaCasse | LB | 8 | 4 | 0.0 | 0 | 0 | 0 |
| Keith O'Neil | LB | 8 | 7 | 0.0 | 0 | 0 | 0 |
| Montae Reagor | DE | 7 | 5 | 1.0 | 0 | 1 | 1 |
| Tyjuan Hagler | OLB | 6 | 2 | 0.0 | 0 | 0 | 0 |
| Tim Jennings | CB | 5 | 5 | 0.0 | 0 | 0 | 0 |
| Adam Vinatieri | K | 4 | 2 | 0.0 | 0 | 0 | 0 |
| Tarik Glenn | OT | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Dan Klecko | FB | 3 | 3 | 0.0 | 0 | 0 | 0 |
| T.J. Rushing | CB | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Jeff Saturday | C | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Justin Snow | LS | 2 | 1 | 0.0 | 0 | 0 | 0 |
| Terrence Wilkins | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jake Scott | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Dominic Rhodes | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Bryan Fletcher | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Reggie Wayne | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Dallas Clark | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Dylan Gandy | C | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Joseph Addai | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |