Franchise 58 seasons 473–417–7 all-time 23 playoff trips 3 Super Bowls
2007 players
Passing
| Damon Huard | 332 | 206 | 2,257 | 11 | 13 | 6.8 |
| Brodie Croyle | 224 | 127 | 1,227 | 6 | 6 | 5.5 |
| Tyler Thigpen | 6 | 2 | 41 | 0 | 1 | 6.8 |
| Larry Johnson | 1 | 0 | 0 | 0 | 0 | 0.0 |
Rushing
| Larry Johnson | 158 | 559 | 3 | 3.5 |
| Kolby Smith | 112 | 407 | 2 | 3.6 |
| Priest Holmes | 46 | 137 | 0 | 3.0 |
| Jackie Battle | 14 | 47 | 1 | 3.4 |
| Brodie Croyle | 7 | 18 | 0 | 2.6 |
| Gilbert Harris | 9 | 9 | 0 | 1.0 |
| Kris Wilson | 3 | 7 | 0 | 2.3 |
| Jeff Webb | 1 | 5 | 0 | 5.0 |
| Eddie Kennison | 2 | 5 | 0 | 2.5 |
| Jon McGraw | 1 | 4 | 0 | 4.0 |
| Samie Parker | 1 | 2 | 0 | 2.0 |
| Damon Huard | 9 | -1 | 0 | -0.1 |
| Eddie Drummond | 1 | -3 | 0 | -3.0 |
Receiving
| Tony Gonzalez | 99 | 1,172 | 5 | 11.8 |
| Dwayne Bowe | 70 | 995 | 5 | 14.2 |
| Jeff Webb | 28 | 315 | 1 | 11.2 |
| Samie Parker | 24 | 298 | 2 | 12.4 |
| Larry Johnson | 30 | 186 | 1 | 6.2 |
| Kris Wilson | 24 | 180 | 1 | 7.5 |
| Kolby Smith | 22 | 148 | 0 | 6.7 |
| Eddie Kennison | 13 | 101 | 0 | 7.8 |
| Gilbert Harris | 3 | 38 | 0 | 12.7 |
| Priest Holmes | 5 | 17 | 0 | 3.4 |
| Boomer Grigsby | 2 | 14 | 0 | 7.0 |
| Jason Dunn | 2 | 9 | 0 | 4.5 |
| Jackie Battle | 1 | 4 | 0 | 4.0 |
| Jared Allen | 2 | 3 | 2 | 1.5 |
Defense
| Napoleon Harris | MLB | 99 | 66 | 1.5 | 1 | 3 | 0 |
| Donnie Edwards | OLB | 85 | 66 | 2.0 | 1 | 3 | 1 |
| Derrick Johnson | LB | 80 | 69 | 4.0 | 2 | 6 | 3 |
| Bernard Pollard | S | 78 | 62 | 1.0 | 2 | 7 | 1 |
| Patrick Surtain | CB | 54 | 46 | 0.0 | 2 | 6 | 0 |
| Jarrad Page | S | 51 | 35 | 0.0 | 3 | 6 | 1 |
| Jared Allen | DE | 50 | 41 | 15.5 | 0 | 10 | 3 |
| Tamba Hali | OLB | 48 | 36 | 7.5 | 0 | 2 | 2 |
| Ty Law | CB | 44 | 36 | 0.0 | 2 | 13 | 0 |
| Benny Sapp | CB | 29 | 23 | 0.0 | 1 | 4 | 0 |
| Greg Wesley | FS | 27 | 25 | 0.0 | 0 | 3 | 1 |
| Ron Edwards | DT | 23 | 20 | 3.0 | 0 | 1 | 0 |
| Alfonso Boone | DE | 23 | 16 | 1.0 | 0 | 5 | 0 |
| Tyron Brackenridge | CB | 23 | 20 | 0.0 | 0 | 0 | 1 |
| Jimmy Wilkerson | DE | 21 | 17 | 0.5 | 0 | 0 | 0 |
| Keyaron Fox | LB | 18 | 16 | 0.0 | 0 | 0 | 0 |
| Pat Thomas | MLB | 11 | 7 | 0.0 | 0 | 0 | 0 |
| Turk McBride | DE | 11 | 8 | 1.0 | 0 | 1 | 0 |
| Nate Harris | LB | 10 | 7 | 0.0 | 0 | 0 | 0 |
| Jon McGraw | S | 9 | 8 | 0.0 | 0 | 1 | 0 |
| Dimitri Patterson | CB | 8 | 7 | 0.0 | 0 | 0 | 0 |
| Kendrell Bell | OLB | 8 | 6 | 0.0 | 0 | 0 | 0 |
| J.P. Darche | LS | 7 | 7 | 0.0 | 0 | 0 | 0 |
| Tank Tyler | DT | 7 | 4 | 0.0 | 0 | 0 | 0 |
| Rashad Barksdale | DB | 6 | 6 | 0.0 | 0 | 0 | 0 |
| Boomer Grigsby | LB | 5 | 4 | 0.0 | 0 | 0 | 0 |
| Eddie Drummond | WR | 5 | 5 | 0.0 | 0 | 0 | 0 |
| Tony Gonzalez | TE | 4 | 4 | 0.0 | 0 | 0 | 0 |
| Jeff Webb | WR | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Kris Wilson | TE | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Kolby Smith | RB | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Samie Parker | WR | 3 | 3 | 0.0 | 0 | 0 | 0 |
| James Reed | DT | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Bobby Sippio | WR | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Dwayne Bowe | WR | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Johnny Baldwin | LB | 2 | 1 | 0.0 | 0 | 0 | 0 |
| Casey Wiegmann | C | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Damion McIntosh | OT | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Brian Waters | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Kyle Turley | OT | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Chris Terry | OT | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Eddie Kennison | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Priest Holmes | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jason Dunn | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Brodie Croyle | QB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Will Svitek | OT | 1 | 1 | 0.0 | 0 | 0 | 0 |