Franchise 58 seasons 473–417–7 all-time 23 playoff trips 3 Super Bowls
2010 players
Passing
| Matt Cassel | 450 | 262 | 3,116 | 27 | 7 | 6.9 |
| Brodie Croyle | 19 | 8 | 38 | 0 | 1 | 2.0 |
| Tyler Palko | 6 | 4 | 35 | 0 | 0 | 5.8 |
Rushing
| Jamaal Charles | 230 | 1,467 | 5 | 6.4 |
| Thomas Jones | 245 | 896 | 6 | 3.7 |
| Matt Cassel | 33 | 125 | 0 | 3.8 |
| Dexter McCluster | 18 | 71 | 0 | 3.9 |
| Jackie Battle | 20 | 50 | 1 | 2.5 |
| Tyler Palko | 2 | 5 | 0 | 2.5 |
| Javier Arenas | 1 | 5 | 0 | 5.0 |
| Dwayne Bowe | 1 | 4 | 0 | 4.0 |
| Tim Castille | 5 | 3 | 0 | 0.6 |
| Shaun Smith | 1 | 1 | 1 | 1.0 |
Receiving
| Dwayne Bowe | 133 | 72 | 1,162 | 15 | 8.7 |
| Tony Moeaki | 73 | 47 | 556 | 3 | 7.6 |
| Jamaal Charles | 64 | 45 | 468 | 3 | 7.3 |
| Chris Chambers | 43 | 22 | 213 | 1 | 5.0 |
| Dexter McCluster | 39 | 21 | 209 | 1 | 5.4 |
| Terrance Copper | 28 | 18 | 157 | 0 | 5.6 |
| Thomas Jones | 20 | 14 | 122 | 0 | 6.1 |
| Verran Tucker | 19 | 6 | 114 | 1 | 6.0 |
| Leonard Pope | 19 | 10 | 76 | 2 | 4.0 |
| Tim Castille | 12 | 10 | 43 | 0 | 3.6 |
| Jake O'Connell | 4 | 3 | 31 | 0 | 7.8 |
| Mike Cox | 4 | 4 | 27 | 0 | 6.8 |
| Jackie Battle | 3 | 1 | 9 | 0 | 3.0 |
| Mike Vrabel | 2 | 1 | 2 | 1 | 1.0 |