Franchise 58 seasons 473–417–7 all-time 23 playoff trips 3 Super Bowls
2012 players
Passing
| Matt Cassel | 277 | 161 | 1,796 | 6 | 12 | 6.5 |
| Brady Quinn | 197 | 112 | 1,141 | 2 | 8 | 5.8 |
| Peyton Hillis | 1 | 0 | 0 | 0 | 0 | 0.0 |
Rushing
| Jamaal Charles | 285 | 1,509 | 5 | 5.3 |
| Peyton Hillis | 85 | 309 | 1 | 3.6 |
| Shaun Draughn | 59 | 233 | 2 | 3.9 |
| Matt Cassel | 27 | 145 | 1 | 5.4 |
| Dexter McCluster | 12 | 70 | 0 | 5.8 |
| Brady Quinn | 19 | 66 | 0 | 3.5 |
| Cyrus Gray | 7 | 44 | 0 | 6.3 |
| Nate Eachus | 5 | 18 | 0 | 3.6 |
| Terrance Copper | 1 | 1 | 0 | 1.0 |
Receiving
| Dwayne Bowe | 114 | 59 | 801 | 3 | 7.0 |
| Tony Moeaki | 56 | 33 | 453 | 1 | 8.1 |
| Dexter McCluster | 76 | 52 | 452 | 1 | 5.9 |
| Jon Baldwin | 47 | 20 | 325 | 1 | 6.9 |
| Jamaal Charles | 48 | 35 | 236 | 1 | 4.9 |
| Shaun Draughn | 30 | 24 | 158 | 0 | 5.3 |
| Terrance Copper | 12 | 8 | 79 | 0 | 6.6 |
| Steve Breaston | 15 | 7 | 74 | 0 | 4.9 |
| Jamar Newsome | 16 | 5 | 73 | 0 | 4.6 |
| Kevin Boss | 3 | 3 | 65 | 1 | 21.7 |
| Peyton Hillis | 14 | 10 | 62 | 0 | 4.4 |
| Devon Wylie | 12 | 6 | 53 | 0 | 4.4 |
| Steve Maneri | 12 | 5 | 51 | 0 | 4.2 |
| Nate Eachus | 3 | 1 | 19 | 0 | 6.3 |
| Jake O'Connell | 3 | 3 | 18 | 0 | 6.0 |
| Cyrus Gray | 3 | 2 | 18 | 0 | 6.0 |
Defense
| Derrick Johnson | LB | 117 | 102 | 2.0 | 0 | 4 | 3 |
| Eric Berry | DB | 82 | 69 | 0.0 | 1 | 10 | 0 |
| Justin Houston | OLB | 61 | 48 | 10.0 | 1 | 6 | 1 |
| Javier Arenas | CB | 60 | 53 | 0.0 | 0 | 9 | 2 |
| Ropati Pitoitua | DE | 48 | 29 | 2.0 | 0 | 1 | 1 |
| Brandon Flowers | CB | 47 | 39 | 1.0 | 3 | 12 | 0 |
| Tamba Hali | OLB | 47 | 39 | 9.0 | 0 | 2 | 1 |
| Tyson Jackson | DE | 40 | 28 | 3.0 | 0 | 3 | 0 |
| Dontari Poe | DT | 37 | 27 | 0.0 | 0 | 4 | 0 |
| Jovan Belcher | ILB | 36 | 31 | 0.0 | 0 | 1 | 0 |
| Abram Elam | FS | 32 | 26 | 0.0 | 0 | 2 | 0 |
| Kendrick Lewis | S | 26 | 24 | 0.0 | 0 | 1 | 0 |
| Jalil Brown | CB | 25 | 25 | 0.0 | 0 | 2 | 1 |
| Tysyn Hartman | FS | 24 | 19 | 0.0 | 0 | 3 | 0 |
| Brandon Siler | ILB | 19 | 17 | 0.0 | 0 | 0 | 1 |
| Travis Daniels | DB | 16 | 13 | 0.0 | 0 | 1 | 0 |
| Cory Greenwood | LB | 11 | 10 | 0.0 | 0 | 0 | 1 |
| Shaun Smith | DT | 11 | 9 | 0.0 | 0 | 0 | 0 |
| Edgar Jones | DE | 10 | 9 | 0.0 | 0 | 0 | 0 |
| Andy Studebaker | LB | 9 | 8 | 0.0 | 0 | 0 | 0 |
| Shaun Draughn | RB | 6 | 6 | 0.0 | 0 | 0 | 1 |
| Jerrell Powe | NT | 6 | 5 | 0.0 | 0 | 0 | 0 |
| Glenn Dorsey | NT | 5 | 2 | 0.0 | 0 | 0 | 0 |
| Anthony Toribio | DT | 5 | 4 | 0.0 | 0 | 0 | 0 |
| Neiko Thorpe | CB | 5 | 5 | 0.0 | 0 | 0 | 0 |
| Terrance Copper | WR | 5 | 4 | 0.0 | 0 | 0 | 1 |
| Allen Bailey | DE | 5 | 3 | 0.0 | 0 | 0 | 0 |
| Jacques Reeves | CB | 4 | 4 | 0.0 | 0 | 0 | 0 |
| Cyrus Gray | RB | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Tony Moeaki | TE | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Dexter McCluster | WR | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Dwayne Bowe | WR | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Jeff Allen | G | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Josh Bellamy | WR | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Eric Winston | OT | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Nate Eachus | FB | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Ryan Succop | K | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Branden Albert | OT | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Rodney Hudson | C | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Jon Asamoah | G | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Matt Cassel | QB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Thomas Gafford | LS | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jamaal Charles | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jake O'Connell | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Steve Maneri | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jon Baldwin | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jamar Newsome | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Patrick DiMarco | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |