Franchise 77 seasons 591–549–15 all-time 32 playoff trips 2 Super Bowls
2020 players
Passing
| Jared Goff | 552 | 370 | 3,952 | 20 | 13 | 7.2 |
| John Wolford | 38 | 22 | 231 | 0 | 1 | 6.1 |
Rushing
| Cam Akers | 145 | 625 | 2 | 4.3 |
| Darrell Henderson | 138 | 624 | 5 | 4.5 |
| Malcolm Brown | 101 | 419 | 5 | 4.1 |
| Robert Woods | 24 | 155 | 2 | 6.5 |
| Jared Goff | 51 | 99 | 4 | 1.9 |
| John Wolford | 6 | 56 | 0 | 9.3 |
| Cooper Kupp | 4 | 33 | 0 | 8.2 |
| Josh Reynolds | 1 | 5 | 0 | 5.0 |
| Gerald Everett | 1 | 2 | 1 | 2.0 |
| Tyler Higbee | 1 | 1 | 0 | 1.0 |
| Van Jefferson | 1 | -1 | 0 | -1.0 |
Receiving
| Cooper Kupp | 124 | 92 | 974 | 3 | 7.9 |
| Robert Woods | 129 | 90 | 936 | 6 | 7.3 |
| Josh Reynolds | 81 | 52 | 618 | 2 | 7.6 |
| Tyler Higbee | 60 | 44 | 521 | 5 | 8.7 |
| Gerald Everett | 62 | 41 | 417 | 1 | 6.7 |
| Van Jefferson | 31 | 19 | 220 | 1 | 7.1 |
| Malcolm Brown | 33 | 23 | 162 | 0 | 4.9 |
| Darrell Henderson | 24 | 16 | 159 | 1 | 6.6 |
| Cam Akers | 14 | 11 | 123 | 1 | 8.8 |
| Johnny Mundt | 4 | 4 | 53 | 0 | 13.2 |
Defense
| John Johnson | DB | 101 | 69 | 0.0 | 1 | 8 | 0 |
| Micah Kiser | LB | 77 | 44 | 0.0 | 0 | 3 | 1 |
| Troy Reeder | LB | 76 | 48 | 3.0 | 0 | 2 | 0 |
| Troy Hill | CB | 74 | 52 | 0.0 | 3 | 10 | 1 |
| Jordan Fuller | SAF | 55 | 37 | 0.0 | 3 | 5 | 0 |
| Sebastian Joseph-Day | DE | 52 | 32 | 1.0 | 0 | 3 | 1 |
| Leonard Floyd | DE | 50 | 26 | 10.5 | 0 | 1 | 1 |
| Michael Brockers | DT | 49 | 19 | 5.0 | 0 | 0 | 0 |
| Kenny Young | ILB | 49 | 28 | 1.0 | 1 | 2 | 0 |
| Aaron Donald | DL | 44 | 26 | 13.5 | 0 | 1 | 4 |
| Taylor Rapp | SAF | 43 | 31 | 0.0 | 1 | 3 | 1 |
| Jalen Ramsey | CB | 42 | 34 | 0.0 | 1 | 9 | 0 |
| Darious Williams | CB | 42 | 35 | 0.0 | 4 | 14 | 0 |
| Justin Hollins | LB | 28 | 18 | 3.0 | 0 | 1 | 1 |
| Samson Ebukam | DE | 28 | 15 | 4.5 | 0 | 1 | 1 |
| Morgan Fox | DE | 21 | 15 | 6.0 | 0 | 2 | 1 |
| Greg Gaines | DT | 17 | 8 | 1.5 | 0 | 0 | 0 |
| Nick Scott | SAF | 16 | 11 | 0.0 | 0 | 0 | 0 |
| Ogbo Okoronkwo | DE | 11 | 7 | 1.0 | 0 | 1 | 0 |
| Nsimba Webster | WR | 10 | 7 | 0.0 | 0 | 0 | 0 |
| A'Shawn Robinson | DE | 10 | 4 | 0.0 | 0 | 1 | 0 |
| Terrell Burgess | SAF | 8 | 7 | 0.0 | 0 | 1 | 0 |
| David Long | DB | 7 | 6 | 0.0 | 0 | 0 | 0 |
| Derek Rivers | DE | 5 | 2 | 1.5 | 0 | 0 | 0 |
| Terrell Lewis | LB | 5 | 3 | 2.0 | 0 | 0 | 0 |
| Jachai Polite | LB | 4 | 3 | 1.0 | 0 | 0 | 0 |
| Xavier Jones | RB | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Cooper Kupp | WR | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Malcolm Brown | RB | 3 | 3 | 0.0 | 0 | 0 | 0 |
| JuJu Hughes | S | 3 | 1 | 0.0 | 0 | 0 | 0 |
| Van Jefferson | WR | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Natrez Patrick | ILB | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Johnny Mundt | TE | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Robert Woods | WR | 2 | 2 | 0.0 | 0 | 0 | 0 |
| J.R. Reed | SAF | 2 | 0 | 0.0 | 0 | 0 | 0 |
| Austin Corbett | C | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Kai Forbath | K | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Josh Reynolds | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Gerald Everett | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Tyler Higbee | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jared Goff | QB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Marquise Copeland | DT | 1 | 1 | 0.0 | 0 | 0 | 0 |