Franchise 57 seasons 427–465–5 all-time 17 playoff trips 0 Super Bowls
2024 players
Passing
| Justin Herbert | 504 | 332 | 3,870 | 23 | 3 | 7.7 |
| Taylor Heinicke | 5 | 3 | 28 | 0 | 0 | 5.6 |
| J.K. Scott | 1 | 1 | 3 | 0 | 0 | 3.0 |
Rushing
| J.K. Dobbins | 195 | 905 | 9 | 4.6 |
| Gus Edwards | 101 | 365 | 4 | 3.6 |
| Justin Herbert | 69 | 306 | 2 | 4.4 |
| Kimani Vidal | 43 | 155 | 0 | 3.6 |
| Hassan Haskins | 34 | 89 | 2 | 2.6 |
| Derius Davis | 12 | 39 | 0 | 3.2 |
| Taylor Heinicke | 2 | 20 | 0 | 10.0 |
| Quentin Johnston | 3 | 6 | 0 | 2.0 |
| J.K. Scott | 1 | 0 | 0 | 0.0 |
| Jalen Reagor | 3 | -3 | 0 | -1.0 |
Receiving
| Ladd McConkey | 112 | 82 | 1,149 | 7 | 10.3 |
| Quentin Johnston | 91 | 55 | 711 | 8 | 7.8 |
| Josh Palmer | 65 | 39 | 584 | 1 | 9.0 |
| Will Dissly | 64 | 50 | 481 | 2 | 7.5 |
| Stone Smartt | 19 | 16 | 208 | 0 | 10.9 |
| J.K. Dobbins | 38 | 32 | 153 | 0 | 4.0 |
| Derius Davis | 17 | 13 | 112 | 2 | 6.6 |
| Simi Fehoko | 16 | 6 | 106 | 0 | 6.6 |
| Jalen Reagor | 12 | 7 | 100 | 0 | 8.3 |
| Hayden Hurst | 13 | 8 | 73 | 0 | 5.6 |
| Kimani Vidal | 9 | 5 | 62 | 1 | 6.9 |
| Hassan Haskins | 3 | 3 | 49 | 1 | 16.3 |
| Tucker Fisk | 8 | 7 | 39 | 0 | 4.9 |
| DJ Chark | 10 | 4 | 31 | 1 | 3.1 |
| Scott Matlock | 5 | 4 | 28 | 0 | 5.6 |
| Eric Tomlinson | 4 | 2 | 9 | 0 | 2.2 |
| Gus Edwards | 5 | 3 | 6 | 0 | 1.2 |
Defense
| Daiyan Henley | LB | 135 | 72 | 1.0 | 1 | 8 | 0 |
| Derwin James | FS | 89 | 56 | 5.5 | 1 | 7 | 0 |
| Elijah Molden | CB | 70 | 38 | 0.0 | 3 | 7 | 0 |
| Tarheeb Still | CB | 60 | 43 | 0.5 | 4 | 10 | 0 |
| Troy Dye | LB | 57 | 33 | 1.5 | 0 | 0 | 0 |
| Kristian Fulton | CB | 46 | 34 | 0.0 | 1 | 7 | 0 |
| Denzel Perryman | MLB | 46 | 30 | 1.0 | 0 | 0 | 0 |
| Alohi Gilman | SAF | 43 | 27 | 1.0 | 1 | 4 | 0 |
| Tuli Tuipulotu | LB | 40 | 25 | 8.5 | 0 | 2 | 1 |
| Marcus Maye | FS | 39 | 16 | 0.0 | 1 | 3 | 0 |
| Poona Ford | DT | 38 | 23 | 3.0 | 1 | 4 | 0 |
| Khalil Mack | OLB | 37 | 18 | 6.0 | 0 | 9 | 2 |
| Cam Hart | CB | 37 | 28 | 0.5 | 0 | 7 | 1 |
| Otito Ogbonnia | DT | 34 | 11 | 0.0 | 0 | 1 | 0 |
| Teair Tart | DT | 29 | 15 | 1.0 | 1 | 2 | 1 |
| Junior Colson | LB | 28 | 14 | 0.0 | 0 | 1 | 0 |
| Bud Dupree | OLB | 27 | 17 | 6.0 | 1 | 2 | 1 |
| Tony Jefferson | S | 27 | 17 | 0.0 | 0 | 0 | 0 |
| Morgan Fox | DE | 24 | 16 | 3.5 | 0 | 1 | 0 |
| Joey Bosa | DE | 21 | 16 | 5.0 | 0 | 0 | 2 |
| Nick Niemann | LB | 21 | 11 | 0.0 | 0 | 1 | 0 |
| Ja'Sir Taylor | CB | 20 | 10 | 0.0 | 0 | 5 | 0 |
| Asante Samuel Jr. | CB | 13 | 11 | 0.0 | 0 | 2 | 0 |
| Deane Leonard | CB | 8 | 6 | 0.0 | 0 | 3 | 0 |
| Scott Matlock | DT | 8 | 3 | 1.0 | 0 | 1 | 0 |
| Hassan Haskins | RB | 6 | 2 | 0.0 | 0 | 0 | 0 |
| Shaquille Quarterman | LB | 6 | 5 | 0.0 | 0 | 0 | 0 |
| Dicaprio Bootle | CB | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Caleb Murphy | LB | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Kendall Williamson | SAF | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Stone Smartt | TE | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Justin Eboigbe | DT | 2 | 1 | 0.0 | 0 | 0 | 0 |
| Eli Apple | CB | 2 | 2 | 0.0 | 0 | 1 | 0 |
| Cameron Dicker | K | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Ladd McConkey | WR | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Simi Fehoko | WR | 2 | 1 | 0.0 | 0 | 0 | 0 |
| Josh Harris | LS | 1 | 0 | 0.0 | 0 | 0 | 0 |
| Bradley Bozeman | C | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Justin Herbert | QB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Quentin Johnston | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Tucker Fisk | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |