Franchise 57 seasons 498–384–2 all-time 25 playoff trips 2 Super Bowls
2001 players
Passing
| Jay Fiedler | 449 | 272 | 3,248 | 20 | 19 | 7.2 |
| Ray Lucas | 3 | 2 | 45 | 0 | 0 | 15.0 |
Rushing
| Lamar Smith | 313 | 968 | 6 | 3.1 |
| Jay Fiedler | 73 | 321 | 4 | 4.4 |
| Travis Minor | 59 | 281 | 2 | 4.8 |
| James McKnight | 6 | 39 | 0 | 6.5 |
| J.J. Johnson | 5 | 22 | 0 | 4.4 |
| Rob Konrad | 5 | 22 | 1 | 4.4 |
| Dedric Ward | 2 | 21 | 0 | 10.5 |
| Ray Lucas | 8 | 6 | 1 | 0.8 |
| Olindo Mare | 1 | -5 | 0 | -5.0 |
| Chris Chambers | 1 | -11 | 0 | -11.0 |
Receiving
| Chris Chambers | 90 | 48 | 883 | 7 | 9.8 |
| James McKnight | 90 | 55 | 684 | 3 | 7.6 |
| Oronde Gadsden | 92 | 55 | 674 | 3 | 7.3 |
| Travis Minor | 37 | 29 | 263 | 1 | 7.1 |
| Lamar Smith | 35 | 30 | 234 | 2 | 6.7 |
| Jed Weaver | 25 | 18 | 215 | 2 | 8.6 |
| Dedric Ward | 40 | 21 | 209 | 0 | 5.2 |
| Jeff Ogden | 8 | 6 | 73 | 1 | 9.1 |
| Rob Konrad | 13 | 5 | 52 | 1 | 4.0 |
| Hunter Goodwin | 10 | 4 | 27 | 0 | 2.7 |
| J.J. Johnson | 6 | 4 | 21 | 0 | 3.5 |
Defense
| Zach Thomas | ILB | 135 | 75 | 3.0 | 2 | 4 | 2 |
| Brock Marion | FS | 73 | 49 | 0.0 | 5 | 7 | 2 |
| Brian Walker | FS | 72 | 45 | 0.0 | 1 | 5 | 0 |
| Jason Taylor | OLB | 63 | 40 | 8.5 | 1 | 8 | 4 |
| Derrick Rodgers | OLB | 61 | 34 | 1.0 | 0 | 7 | 0 |
| Terry Cousin | DB | 58 | 43 | 2.0 | 0 | 5 | 2 |
| Morlon Greenwood | OLB | 53 | 25 | 1.5 | 0 | 0 | 0 |
| Patrick Surtain | CB | 51 | 41 | 1.0 | 3 | 16 | 2 |
| Tim Bowens | DT | 40 | 22 | 3.0 | 0 | 2 | 0 |
| Kenny Mixon | DE | 39 | 20 | 2.0 | 1 | 2 | 0 |
| Arturo Freeman | DB | 30 | 21 | 1.0 | 1 | 7 | 0 |
| Lorenzo Bromell | DE | 28 | 16 | 6.5 | 0 | 0 | 3 |
| Daryl Gardener | DT | 25 | 14 | 4.0 | 0 | 2 | 1 |
| Sam Madison | CB | 23 | 16 | 0.0 | 2 | 13 | 0 |
| Tommy Hendricks | LB | 22 | 15 | 0.0 | 0 | 0 | 0 |
| Twan Russell | LB | 21 | 11 | 0.0 | 0 | 0 | 0 |
| Scott Galyon | LB | 18 | 8 | 1.0 | 1 | 1 | 0 |
| Ernest Grant | DT | 16 | 8 | 0.5 | 0 | 0 | 0 |
| Jermaine Haley | DT | 16 | 8 | 0.5 | 0 | 1 | 0 |
| Shawn Wooden | DB | 14 | 14 | 0.0 | 0 | 0 | 0 |
| Jamar Fletcher | DB | 10 | 8 | 0.0 | 0 | 0 | 0 |
| David Bowens | ILB | 9 | 7 | 1.0 | 0 | 5 | 1 |
| Travis Minor | RB | 9 | 5 | 0.0 | 0 | 0 | 0 |
| Chris Chambers | WR | 8 | 8 | 0.0 | 0 | 0 | 0 |
| Scott McGarrahan | DB | 7 | 3 | 0.0 | 0 | 0 | 0 |
| Jeff Ogden | WR | 5 | 3 | 0.0 | 0 | 0 | 1 |
| Ed Perry | TE | 4 | 2 | 0.0 | 0 | 0 | 0 |
| James McKnight | WR | 2 | 2 | 0.0 | 0 | 0 | 1 |
| Adewale Ogunleye | DE | 2 | 0 | 0.5 | 0 | 0 | 0 |
| Damian Gregory | DT | 2 | 1 | 0.0 | 0 | 0 | 0 |
| Jay Fiedler | QB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Oronde Gadsden | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Rob Konrad | FB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Henry Taylor | DT | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Lamar Smith | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Tim Ruddy | C | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jed Weaver | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Trent Gamble | DB | 1 | 0 | 0.0 | 0 | 0 | 0 |
| Ray Green | DB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Todd Wade | OT | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Deon Dyer | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |