Franchise 60 seasons 424–497–5 all-time 14 playoff trips 1 Super Bowls
2005 players
Passing
| Aaron Brooks | 431 | 240 | 2,882 | 13 | 17 | 6.7 |
| Todd Bouman | 122 | 68 | 722 | 2 | 7 | 5.9 |
Rushing
| Antowain Smith | 166 | 659 | 3 | 4.0 |
| Aaron Stecker | 95 | 363 | 0 | 3.8 |
| Deuce McAllister | 93 | 335 | 3 | 3.6 |
| Aaron Brooks | 45 | 281 | 2 | 6.2 |
| Anthony Thomas | 43 | 92 | 0 | 2.1 |
| Todd Bouman | 8 | 15 | 0 | 1.9 |
| Mike Karney | 6 | 12 | 0 | 2.0 |
| Devery Henderson | 1 | 9 | 0 | 9.0 |
| Donte' Stallworth | 2 | 2 | 0 | 1.0 |
Receiving
| Donte' Stallworth | 70 | 945 | 7 | 13.5 |
| Joe Horn | 49 | 654 | 1 | 13.3 |
| Az-Zahir Hakim | 34 | 489 | 2 | 14.4 |
| Zach Hilton | 35 | 396 | 1 | 11.3 |
| Devery Henderson | 22 | 343 | 3 | 15.6 |
| Aaron Stecker | 35 | 281 | 0 | 8.0 |
| Ernie Conwell | 13 | 165 | 1 | 12.7 |
| Deuce McAllister | 17 | 117 | 0 | 6.9 |
| Nate Poole | 3 | 63 | 0 | 21.0 |
| Mike Karney | 10 | 61 | 0 | 6.1 |
| Antowain Smith | 12 | 46 | 0 | 3.8 |
| Lamont Hall | 6 | 36 | 0 | 6.0 |
| Anthony Thomas | 4 | 13 | 0 | 3.2 |