Franchise 60 seasons 424–497–5 all-time 14 playoff trips 1 Super Bowls
2022 players
Passing
| Andy Dalton | 378 | 252 | 2,871 | 18 | 9 | 7.6 |
| Jameis Winston | 115 | 73 | 858 | 4 | 5 | 7.5 |
| Taysom Hill | 19 | 13 | 240 | 2 | 0 | 12.6 |
Rushing
| Alvin Kamara | 223 | 897 | 2 | 4.0 |
| Taysom Hill | 96 | 575 | 7 | 6.0 |
| Eno Benjamin | 77 | 313 | 2 | 4.1 |
| Mark Ingram | 62 | 233 | 1 | 3.8 |
| Rashid Shaheed | 4 | 57 | 1 | 14.2 |
| Andy Dalton | 30 | 54 | 0 | 1.8 |
| Dwayne Washington | 11 | 38 | 0 | 3.5 |
| David Johnson | 12 | 24 | 0 | 2.0 |
| Jameis Winston | 5 | 16 | 0 | 3.2 |
| Adam Prentice | 4 | 9 | 0 | 2.2 |
| Jordan Howard | 1 | 1 | 0 | 1.0 |
Receiving
| Chris Olave | 119 | 72 | 1,042 | 4 | 8.8 |
| Juwan Johnson | 65 | 42 | 508 | 7 | 7.8 |
| Alvin Kamara | 77 | 57 | 490 | 2 | 6.4 |
| Rashid Shaheed | 34 | 28 | 488 | 2 | 14.4 |
| Tre'Quan Smith | 27 | 19 | 278 | 1 | 10.3 |
| Jarvis Landry | 39 | 25 | 272 | 1 | 7.0 |
| Adam Trautman | 22 | 18 | 207 | 1 | 9.4 |
| Eno Benjamin | 34 | 25 | 193 | 0 | 5.7 |
| Michael Thomas | 22 | 16 | 171 | 3 | 7.8 |
| Marquez Callaway | 32 | 16 | 158 | 1 | 4.9 |
| Taysom Hill | 13 | 9 | 77 | 2 | 5.9 |
| Kevin White | 5 | 2 | 74 | 0 | 14.8 |
| Mark Ingram | 18 | 16 | 68 | 0 | 3.8 |
| David Johnson | 4 | 4 | 47 | 0 | 11.8 |
| Keith Kirkwood | 4 | 2 | 18 | 0 | 4.5 |
| Deonte Harty | 2 | 2 | 13 | 0 | 6.5 |
| Adam Prentice | 3 | 3 | 9 | 0 | 3.0 |
| Dwayne Washington | 1 | 1 | 7 | 0 | 7.0 |
Defense
| Demario Davis | OLB | 101 | 46 | 6.5 | 1 | 6 | 0 |
| Tyrann Mathieu | FS | 85 | 58 | 1.0 | 3 | 8 | 1 |
| Pete Werner | LB | 79 | 55 | 0.0 | 0 | 3 | 2 |
| Kaden Elliss | LB | 70 | 35 | 7.0 | 0 | 2 | 2 |
| Cameron Jordan | DE | 58 | 32 | 8.5 | 0 | 2 | 2 |
| Paulson Adebo | CB | 56 | 47 | 0.0 | 0 | 7 | 0 |
| Marcus Maye | FS | 52 | 34 | 0.0 | 0 | 2 | 1 |
| Carl Granderson | DE | 49 | 26 | 5.5 | 0 | 0 | 0 |
| Shy Tuttle | DT | 44 | 21 | 2.0 | 0 | 5 | 0 |
| Alontae Taylor | CB | 44 | 37 | 0.0 | 0 | 11 | 0 |
| David Onyemata | DT | 36 | 18 | 5.0 | 0 | 1 | 0 |
| Bradley Roby | CB | 35 | 28 | 0.0 | 0 | 5 | 0 |
| Marshon Lattimore | CB | 29 | 20 | 0.0 | 1 | 4 | 0 |
| Kentavius Street | DE | 28 | 12 | 3.5 | 0 | 1 | 0 |
| Chris Harris | CB | 27 | 24 | 1.0 | 0 | 3 | 1 |
| Tanoh Kpassagnon | DE | 26 | 13 | 2.0 | 0 | 0 | 0 |
| Justin Evans | S | 26 | 14 | 0.0 | 0 | 2 | 1 |
| Marcus Davenport | DE | 25 | 12 | 0.5 | 0 | 0 | 0 |
| P.J. Williams | S | 25 | 16 | 0.0 | 0 | 2 | 0 |
| Daniel Sorensen | DB | 24 | 14 | 0.0 | 2 | 3 | 0 |
| Malcolm Roach | DT | 23 | 11 | 1.0 | 0 | 0 | 0 |
| J.T. Gray | DB | 17 | 9 | 2.5 | 0 | 0 | 0 |
| Payton Turner | DE | 13 | 8 | 2.0 | 0 | 0 | 0 |
| Zack Baun | LB | 11 | 6 | 0.0 | 0 | 0 | 0 |
| Chase Hansen | LB | 9 | 5 | 0.0 | 0 | 0 | 0 |
| Andrew Dowell | LB | 7 | 4 | 0.0 | 0 | 0 | 2 |
| Ty Summers | LB | 6 | 4 | 0.0 | 0 | 0 | 0 |
| Zach Wood | LS | 4 | 2 | 0.0 | 0 | 0 | 0 |
| Kevin White | WR | 3 | 1 | 0.0 | 0 | 0 | 0 |
| Adam Prentice | RB | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Chris Olave | WR | 3 | 3 | 0.0 | 0 | 0 | 1 |
| Bryce Thompson | CB | 2 | 0 | 0.0 | 0 | 0 | 0 |
| Jabari Zuniga | DE | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Juwan Johnson | TE | 2 | 1 | 0.0 | 0 | 0 | 0 |
| Erik McCoy | C | 2 | 1 | 0.0 | 0 | 0 | 0 |
| Tre'Quan Smith | WR | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Andy Dalton | QB | 1 | 0 | 0.0 | 0 | 0 | 0 |
| Dwayne Washington | RB | 1 | 0 | 0.0 | 0 | 0 | 0 |
| Christian Ringo | DE | 1 | 0 | 0.0 | 0 | 0 | 0 |
| James Hurst | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jarvis Landry | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Isaac Yiadom | CB | 1 | 0 | 0.0 | 0 | 0 | 0 |
| Cesar Ruiz | C | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Calvin Throckmorton | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Eno Benjamin | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |