Franchise 77 seasons 576–546–19 all-time 29 playoff trips 2 Super Bowls
2010 players
Passing
| Mike Vick | 372 | 233 | 3,018 | 21 | 6 | 8.1 |
| Kevin Kolb | 189 | 115 | 1,197 | 7 | 7 | 6.3 |
Rushing
| LeSean McCoy | 207 | 1,080 | 7 | 5.2 |
| Mike Vick | 99 | 676 | 9 | 6.8 |
| Jerome Harrison | 71 | 330 | 1 | 4.6 |
| DeSean Jackson | 16 | 104 | 1 | 6.5 |
| Eldra Buckley | 21 | 67 | 0 | 3.2 |
| Kevin Kolb | 16 | 66 | 0 | 4.1 |
| Jeremy Maclin | 3 | 36 | 0 | 12.0 |
| Chad Hall | 9 | 29 | 0 | 3.2 |
| Leonard Weaver | 1 | 0 | 0 | 0.0 |
Receiving
| DeSean Jackson | 96 | 47 | 1,056 | 6 | 11.0 |
| Jeremy Maclin | 115 | 70 | 964 | 10 | 8.4 |
| LeSean McCoy | 90 | 78 | 592 | 2 | 6.6 |
| Jason Avant | 75 | 51 | 573 | 1 | 7.6 |
| Brent Celek | 79 | 42 | 511 | 4 | 6.5 |
| Owen Schmitt | 24 | 19 | 136 | 1 | 5.7 |
| Riley Cooper | 18 | 7 | 116 | 1 | 6.4 |
| Chad Hall | 18 | 11 | 115 | 1 | 6.4 |
| Jerome Harrison | 13 | 12 | 85 | 0 | 6.5 |
| Clay Harbor | 15 | 9 | 72 | 1 | 4.8 |
| Garrett Mills | 3 | 2 | 19 | 0 | 6.3 |
| Eldra Buckley | 2 | 1 | 10 | 0 | 5.0 |
| Todd Herremans | 1 | 1 | 2 | 1 | 2.0 |
| Mike McGlynn | 1 | 1 | 1 | 0 | 1.0 |
Defense
| Quintin Mikell | S | 79 | 68 | 1.0 | 3 | 15 | 1 |
| Trent Cole | OLB | 60 | 45 | 10.0 | 0 | 2 | 1 |
| Stewart Bradley | LB | 56 | 45 | 1.0 | 1 | 6 | 0 |
| Ernie Sims | OLB | 51 | 44 | 2.0 | 0 | 5 | 1 |
| Dimitri Patterson | CB | 50 | 48 | 1.0 | 4 | 11 | 0 |
| Moise Fokou | LB | 45 | 38 | 1.0 | 0 | 1 | 1 |
| Nate Allen | S | 45 | 39 | 2.0 | 3 | 8 | 1 |
| Kurt Coleman | S | 35 | 30 | 0.0 | 1 | 2 | 0 |
| Mike Patterson | DT | 34 | 26 | 2.0 | 0 | 0 | 0 |
| Jamar Chaney | LB | 34 | 25 | 0.0 | 0 | 1 | 1 |
| Omar Gaither | MLB | 33 | 29 | 0.0 | 0 | 0 | 0 |
| Joselio Hanson | FS | 33 | 28 | 0.0 | 1 | 7 | 0 |
| Antonio Dixon | DT | 27 | 22 | 2.0 | 0 | 2 | 0 |
| Darryl Tapp | DE | 26 | 25 | 3.0 | 0 | 4 | 0 |
| Asante Samuel | CB | 25 | 21 | 0.0 | 7 | 14 | 0 |
| Akeem Jordan | ILB | 24 | 20 | 0.0 | 0 | 1 | 0 |
| Trevard Lindley | DB | 23 | 22 | 0.0 | 1 | 1 | 0 |
| Brodrick Bunkley | NT | 19 | 16 | 0.0 | 0 | 1 | 0 |
| Juqua Parker | DE | 17 | 14 | 6.0 | 0 | 2 | 1 |
| Colt Anderson | DB | 17 | 17 | 0.0 | 0 | 0 | 0 |
| Ellis Hobbs | CB | 16 | 12 | 0.0 | 1 | 4 | 0 |
| Trevor Laws | DT | 15 | 13 | 3.0 | 1 | 5 | 1 |
| Brandon Graham | DE | 12 | 11 | 3.0 | 0 | 0 | 2 |
| Keenan Clayton | LB | 10 | 7 | 0.0 | 0 | 1 | 0 |
| Eldra Buckley | RB | 6 | 6 | 0.0 | 0 | 0 | 1 |
| Brandon Hughes | DB | 5 | 5 | 0.0 | 0 | 0 | 0 |
| Jason Avant | WR | 4 | 4 | 0.0 | 0 | 0 | 0 |
| Jamar Adams | DB | 3 | 2 | 0.0 | 0 | 1 | 0 |
| Riley Cooper | WR | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Sav Rocca | P | 3 | 2 | 0.0 | 0 | 0 | 0 |
| David Akers | K | 2 | 1 | 0.0 | 0 | 0 | 0 |
| Jason Peters | OT | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Daniel Te'o-Nesheim | DE | 2 | 2 | 1.0 | 0 | 0 | 0 |
| Chad Hall | WR | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Jon Dorenbos | LS | 2 | 1 | 0.0 | 0 | 0 | 0 |
| Jeremy Maclin | WR | 2 | 2 | 0.0 | 0 | 0 | 0 |
| King Dunlap | OT | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Owen Schmitt | FB | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Max Jean-Gilles | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Todd Herremans | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| DeSean Jackson | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Mike McGlynn | OT | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jeremy Clark | DT | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Kevin Kolb | QB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jerome Harrison | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Garrett Mills | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| LeSean McCoy | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jorrick Calvin | DB | 1 | 1 | 0.0 | 0 | 0 | 0 |