Franchise 77 seasons 637–489–14 all-time 35 playoff trips 6 Super Bowls
2023 players
Passing
| Kenny Pickett | 324 | 201 | 2,070 | 6 | 4 | 6.4 |
| Mason Rudolph | 74 | 55 | 719 | 3 | 0 | 9.7 |
| Mitchell Trubisky | 107 | 67 | 632 | 4 | 5 | 5.9 |
| Connor Heyward | 1 | 0 | 0 | 0 | 0 | 0.0 |
Rushing
| Najee Harris | 255 | 1,035 | 8 | 4.1 |
| Jaylen Warren | 149 | 784 | 4 | 5.3 |
| Calvin Austin III | 11 | 57 | 1 | 5.2 |
| Mitchell Trubisky | 16 | 54 | 2 | 3.4 |
| Kenny Pickett | 42 | 54 | 1 | 1.3 |
| George Pickens | 3 | 18 | 0 | 6.0 |
| Mason Rudolph | 10 | 8 | 0 | 0.8 |
| Connor Heyward | 1 | 0 | 0 | 0.0 |
Receiving
| George Pickens | 106 | 63 | 1,140 | 5 | 10.8 |
| Diontae Johnson | 87 | 51 | 717 | 5 | 8.2 |
| Jaylen Warren | 74 | 61 | 370 | 0 | 5.0 |
| Pat Freiermuth | 47 | 32 | 308 | 2 | 6.6 |
| Allen Robinson | 49 | 34 | 280 | 0 | 5.7 |
| Calvin Austin III | 30 | 17 | 180 | 1 | 6.0 |
| Najee Harris | 38 | 29 | 170 | 0 | 4.5 |
| Connor Heyward | 34 | 23 | 167 | 0 | 4.9 |
| Darnell Washington | 10 | 7 | 61 | 0 | 6.1 |
| Miles Boykin | 4 | 3 | 17 | 0 | 4.2 |
| Anthony McFarland | 2 | 2 | 11 | 0 | 5.5 |