Franchise 51 seasons 420–381–1 all-time 21 playoff trips 2 Super Bowls
2006 players
Passing
| Matt Hasselbeck | 371 | 210 | 2,442 | 18 | 15 | 6.6 |
| Seneca Wallace | 141 | 82 | 927 | 8 | 7 | 6.6 |
Rushing
| Shaun Alexander | 252 | 896 | 7 | 3.6 |
| Maurice Morris | 161 | 604 | 0 | 3.8 |
| Mack Strong | 33 | 149 | 1 | 4.5 |
| Seneca Wallace | 13 | 119 | 0 | 9.2 |
| Matt Hasselbeck | 18 | 110 | 0 | 6.1 |
| Deion Branch | 4 | 30 | 0 | 7.5 |
| Marquis Weeks | 3 | 8 | 0 | 2.7 |
| Bobby Engram | 1 | 4 | 0 | 4.0 |
Receiving
| Darrell Jackson | 63 | 956 | 10 | 15.2 |
| Deion Branch | 53 | 725 | 4 | 13.7 |
| D.J. Hackett | 45 | 610 | 4 | 13.6 |
| Bobby Engram | 24 | 290 | 1 | 12.1 |
| Jerramy Stevens | 22 | 231 | 4 | 10.5 |
| Nate Burleson | 18 | 192 | 2 | 10.7 |
| Mack Strong | 29 | 159 | 0 | 5.5 |
| Itula Mili | 10 | 69 | 0 | 6.9 |
| Shaun Alexander | 12 | 48 | 0 | 4.0 |
| Maurice Morris | 11 | 46 | 0 | 4.2 |
| Will Heller | 4 | 32 | 1 | 8.0 |
| Josh Parry | 1 | 11 | 0 | 11.0 |
Defense
| Lofa Tatupu | MLB | 94 | 64 | 1.5 | 1 | 7 | 2 |
| Ken Hamlin | DB | 76 | 55 | 2.0 | 3 | 11 | 1 |
| Julian Peterson | OLB | 72 | 54 | 10.0 | 1 | 6 | 1 |
| Leroy Hill | OLB | 70 | 48 | 2.0 | 0 | 2 | 1 |
| Kelly Herndon | DB | 61 | 43 | 0.0 | 1 | 16 | 1 |
| Marcus Trufant | CB | 59 | 51 | 0.0 | 1 | 11 | 2 |
| Jordan Babineaux | S | 49 | 37 | 0.0 | 1 | 4 | 0 |
| Kelly Jennings | DB | 35 | 32 | 0.0 | 1 | 6 | 1 |
| Michael Boulware | DB | 34 | 26 | 0.0 | 2 | 6 | 1 |
| Bryce Fisher | DE | 33 | 24 | 4.0 | 0 | 0 | 0 |
| Grant Wistrom | DE | 28 | 21 | 4.0 | 0 | 2 | 1 |
| Darryl Tapp | DE | 27 | 16 | 3.0 | 1 | 1 | 1 |
| Chartric Darby | DT | 26 | 17 | 3.5 | 0 | 0 | 0 |
| Rocky Bernard | DT | 25 | 13 | 3.5 | 0 | 1 | 2 |
| Russell Davis | DT | 24 | 18 | 3.0 | 0 | 0 | 0 |
| Kevin Bentley | LB | 21 | 14 | 0.0 | 0 | 3 | 1 |
| Jimmy Williams | DB | 11 | 8 | 0.0 | 0 | 2 | 0 |
| Josh Scobey | RB | 11 | 10 | 0.0 | 0 | 0 | 0 |
| Craig Terrill | DT | 11 | 6 | 3.0 | 0 | 0 | 0 |
| Joe Tafoya | DE | 10 | 6 | 0.0 | 0 | 1 | 0 |
| Niko Koutouvides | LB | 9 | 6 | 0.0 | 0 | 0 | 0 |
| Lance Laury | LB | 9 | 6 | 0.0 | 0 | 0 | 0 |
| Oliver Celestin | DB | 8 | 7 | 0.0 | 0 | 0 | 0 |
| D.D. Lewis | LB | 8 | 7 | 1.0 | 0 | 0 | 1 |
| Marcus Tubbs | DT | 6 | 3 | 0.5 | 0 | 0 | 0 |
| Josh Parry | FB | 6 | 5 | 0.0 | 0 | 0 | 0 |
| Marquis Weeks | RB | 5 | 3 | 0.0 | 0 | 0 | 1 |
| Darrell Jackson | WR | 5 | 5 | 0.0 | 0 | 0 | 0 |
| Will Heller | TE | 5 | 4 | 0.0 | 0 | 0 | 0 |
| Deion Branch | WR | 4 | 4 | 0.0 | 0 | 0 | 1 |
| Mack Strong | FB | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Robert Pollard | DE | 3 | 0 | 0.0 | 0 | 0 | 0 |
| Bennie Joppru | TE | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Robbie Tobeck | C | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Derek Rackley | LS | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Chris Gray | G | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Nate Burleson | WR | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Jerramy Stevens | TE | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Floyd Womack | G | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Josh Brown | K | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Matt Hasselbeck | QB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Bobby Engram | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Maurice Morris | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Seneca Wallace | QB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Sean Locklear | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Marquis Cooper | LB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Chris Spencer | C | 1 | 0 | 0.0 | 0 | 0 | 0 |