Franchise 51 seasons 326–471–1 all-time 15 playoff trips 2 Super Bowls
2010 players
Passing
| Josh Freeman | 474 | 291 | 3,451 | 25 | 6 | 7.3 |
| Josh Johnson | 16 | 14 | 111 | 0 | 0 | 6.9 |
| Earnest Graham | 1 | 1 | 2 | 1 | 0 | 2.0 |
| Micheal Spurlock | 3 | 0 | 0 | 0 | 0 | 0.0 |
Rushing
| LeGarrette Blount | 201 | 1,007 | 6 | 5.0 |
| Cadillac Williams | 125 | 437 | 2 | 3.5 |
| Josh Freeman | 68 | 364 | 0 | 5.4 |
| Earnest Graham | 20 | 99 | 1 | 5.0 |
| Josh Johnson | 4 | 39 | 0 | 9.8 |
| Arrelious Benn | 6 | 35 | 0 | 5.8 |
| Kareem Huggins | 4 | 11 | 0 | 2.8 |
| Preston Parker | 1 | 7 | 0 | 7.0 |
| Sammie Stroughter | 1 | 2 | 0 | 2.0 |
| Kregg Lumpkin | 1 | 0 | 0 | 0.0 |
Receiving
| Mike Williams | 129 | 65 | 964 | 11 | 7.5 |
| Kellen Winslow | 98 | 66 | 730 | 5 | 7.4 |
| Arrelious Benn | 38 | 25 | 395 | 2 | 10.4 |
| Cadillac Williams | 64 | 46 | 355 | 1 | 5.5 |
| Micheal Spurlock | 33 | 17 | 250 | 2 | 7.6 |
| Sammie Stroughter | 38 | 24 | 239 | 0 | 6.3 |
| John Gilmore | 18 | 13 | 160 | 1 | 8.9 |
| Earnest Graham | 19 | 16 | 130 | 1 | 6.8 |
| Dezmon Briscoe | 7 | 6 | 93 | 1 | 13.3 |
| Maurice Stovall | 9 | 7 | 81 | 1 | 9.0 |
| Jerramy Stevens | 5 | 3 | 43 | 0 | 8.6 |
| Preston Parker | 9 | 4 | 42 | 0 | 4.7 |
| Ryan Purvis | 6 | 5 | 38 | 0 | 6.3 |
| LeGarrette Blount | 7 | 5 | 14 | 0 | 2.0 |
| Kregg Lumpkin | 1 | 1 | 12 | 0 | 12.0 |
| Erik Lorig | 2 | 1 | 10 | 0 | 5.0 |
| Kareem Huggins | 2 | 1 | 7 | 0 | 3.5 |
| Donald Penn | 1 | 1 | 1 | 1 | 1.0 |
Defense
| Barrett Ruud | ILB | 99 | 66 | 2.0 | 1 | 4 | 2 |
| Geno Hayes | OLB | 69 | 59 | 4.0 | 1 | 6 | 1 |
| Ronde Barber | FS | 68 | 52 | 1.0 | 3 | 13 | 0 |
| Sean Jones | S | 60 | 41 | 1.0 | 1 | 2 | 0 |
| E.J. Biggers | CB | 51 | 44 | 0.0 | 1 | 11 | 0 |
| Quincy Black | OLB | 50 | 42 | 2.0 | 1 | 4 | 1 |
| Cody Grimm | FS | 49 | 35 | 0.0 | 2 | 2 | 1 |
| Aqib Talib | CB | 36 | 35 | 0.0 | 6 | 11 | 0 |
| Roy Miller | DT | 35 | 20 | 1.0 | 0 | 0 | 0 |
| Stylez White | DE | 31 | 23 | 4.5 | 0 | 0 | 2 |
| Corey Lynch | DB | 30 | 20 | 0.0 | 1 | 2 | 0 |
| Dekoda Watson | LB | 29 | 24 | 0.0 | 0 | 1 | 0 |
| Tim Crowder | DE | 28 | 19 | 3.0 | 0 | 4 | 1 |
| Adam Hayward | OLB | 25 | 18 | 1.0 | 0 | 2 | 0 |
| Gerald McCoy | DT | 20 | 14 | 3.0 | 0 | 5 | 2 |
| Kyle Moore | DE | 17 | 9 | 0.0 | 0 | 0 | 0 |
| Elbert Mack | DB | 13 | 12 | 0.0 | 0 | 0 | 0 |
| Al Woods | DT | 13 | 8 | 0.5 | 0 | 0 | 0 |
| Michael Bennett | DE | 12 | 10 | 1.0 | 0 | 1 | 0 |
| Niko Koutouvides | LB | 11 | 10 | 0.0 | 0 | 0 | 0 |
| Alex Magee | DE | 10 | 8 | 2.0 | 0 | 0 | 1 |
| Arrelious Benn | WR | 9 | 8 | 0.0 | 0 | 0 | 0 |
| Myron Lewis | DB | 9 | 9 | 0.0 | 0 | 3 | 0 |
| Frank Okam | DT | 9 | 7 | 0.0 | 0 | 0 | 0 |
| Tanard Jackson | DB | 7 | 7 | 0.0 | 0 | 0 | 0 |
| Maurice Stovall | WR | 6 | 5 | 0.0 | 0 | 0 | 0 |
| Tyrone McKenzie | LB | 5 | 5 | 0.0 | 0 | 0 | 0 |
| Ryan Sims | DE | 4 | 3 | 0.0 | 0 | 0 | 0 |
| Andrew Economos | LS | 4 | 3 | 0.0 | 0 | 0 | 1 |
| Preston Parker | WR | 3 | 1 | 0.0 | 0 | 0 | 0 |
| Sammie Stroughter | WR | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Mike Williams | WR | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Erik Lorig | FB | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Josh Freeman | QB | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Larry Asante | S | 2 | 2 | 0.0 | 1 | 1 | 0 |
| Brian Price | DT | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Jerramy Stevens | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| John Gilmore | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Micheal Spurlock | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Cadillac Williams | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Kregg Lumpkin | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Vince Anderson | DB | 1 | 0 | 0.0 | 0 | 0 | 0 |
| Kareem Huggins | RB | 1 | 0 | 0.0 | 0 | 0 | 0 |
| Derek Hardman | OT | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Chris Bryan | P | 1 | 1 | 0.0 | 0 | 0 | 0 |
| LeGarrette Blount | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |