Franchise 57 seasons 414–468–2 all-time 20 playoff trips 0 Super Bowls
2016 players
Passing
| Marcus Mariota | 451 | 276 | 3,426 | 26 | 9 | 7.6 |
| Matt Cassel | 51 | 30 | 284 | 2 | 2 | 5.6 |
| DeMarco Murray | 2 | 1 | 10 | 1 | 0 | 5.0 |
Rushing
| DeMarco Murray | 293 | 1,287 | 9 | 4.4 |
| Derrick Henry | 110 | 490 | 5 | 4.5 |
| Marcus Mariota | 60 | 349 | 2 | 5.8 |
| Antonio Andrews | 2 | 15 | 0 | 7.5 |
| Kendall Wright | 1 | 15 | 0 | 15.0 |
| Marc Mariani | 1 | 15 | 0 | 15.0 |
| Delanie Walker | 2 | 11 | 0 | 5.5 |
| Matt Cassel | 4 | 3 | 0 | 0.8 |
| Jalston Fowler | 1 | 3 | 0 | 3.0 |
| Tajae Sharpe | 1 | 1 | 0 | 1.0 |
| Valentino Blake | 1 | -2 | 0 | -2.0 |
Receiving
| Rishard Matthews | 108 | 65 | 945 | 9 | 8.8 |
| Delanie Walker | 102 | 65 | 800 | 7 | 7.8 |
| Tajae Sharpe | 83 | 41 | 522 | 2 | 6.3 |
| Kendall Wright | 43 | 29 | 416 | 3 | 9.7 |
| DeMarco Murray | 67 | 53 | 377 | 3 | 5.6 |
| Harry Douglas | 22 | 15 | 210 | 0 | 9.5 |
| Derrick Henry | 15 | 13 | 137 | 0 | 9.1 |
| Andre Johnson | 23 | 9 | 85 | 2 | 3.7 |
| Anthony Fasano | 14 | 8 | 83 | 2 | 5.9 |
| Phillip Supernaw | 5 | 4 | 62 | 0 | 12.4 |
| Jace Amaro | 4 | 3 | 59 | 0 | 14.8 |
| Jalston Fowler | 2 | 1 | 14 | 0 | 7.0 |
| Taylor Lewan | 1 | 1 | 10 | 1 | 10.0 |
Defense
| Avery Williamson | ILB | 100 | 69 | 2.0 | 1 | 1 | 1 |
| Jason McCourty | S | 66 | 57 | 0.0 | 2 | 12 | 0 |
| Kevin Byard | FS | 58 | 44 | 1.0 | 0 | 4 | 0 |
| Wesley Woodyard | ILB | 56 | 41 | 2.0 | 1 | 5 | 0 |
| Sean Spence | LB | 53 | 36 | 3.0 | 0 | 3 | 1 |
| Daimion Stafford | S | 50 | 40 | 1.0 | 1 | 2 | 0 |
| Brian Orakpo | OLB | 46 | 38 | 10.5 | 0 | 4 | 1 |
| Jurrell Casey | DE | 44 | 31 | 5.0 | 0 | 5 | 0 |
| Valentino Blake | DB | 42 | 35 | 0.0 | 0 | 5 | 0 |
| Perrish Cox | CB | 40 | 35 | 0.0 | 3 | 11 | 0 |
| Da'Norris Searcy | S | 40 | 35 | 0.0 | 1 | 6 | 0 |
| Brice McCain | CB | 38 | 31 | 0.0 | 2 | 10 | 0 |
| Rashad Johnson | FS | 38 | 25 | 0.0 | 0 | 1 | 1 |
| Derrick Morgan | OLB | 33 | 24 | 9.0 | 0 | 1 | 0 |
| Karl Klug | DE | 24 | 11 | 1.5 | 0 | 1 | 0 |
| LeShaun Sims | CB | 21 | 18 | 0.0 | 1 | 3 | 0 |
| DaQuan Jones | DT | 19 | 10 | 1.5 | 0 | 0 | 0 |
| Al Woods | DT | 18 | 14 | 0.0 | 0 | 0 | 0 |
| David Bass | OLB | 16 | 10 | 0.0 | 0 | 0 | 0 |
| Aaron Wallace | LB | 14 | 11 | 1.0 | 0 | 0 | 0 |
| Austin Johnson | NT | 14 | 7 | 0.5 | 0 | 1 | 0 |
| Nate Palmer | LB | 12 | 7 | 0.0 | 0 | 0 | 0 |
| Angelo Blackson | DE | 9 | 4 | 0.0 | 0 | 1 | 0 |
| Antonio Andrews | RB | 5 | 3 | 0.0 | 0 | 0 | 0 |
| Kevin Dodd | OLB | 5 | 5 | 1.0 | 0 | 0 | 0 |
| Phillip Supernaw | TE | 5 | 3 | 0.0 | 0 | 0 | 0 |
| Antwaun Woods | DT | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Beau Brinkley | LS | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Taylor Lewan | OT | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Kalan Reed | DB | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Jalston Fowler | RB | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Delanie Walker | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Dennis Kelly | OT | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Josh Kline | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Justin Staples | LB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Kendall Wright | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Mehdi Abdesmad | DE | 1 | 1 | 0.0 | 0 | 0 | 0 |