Regular season and playoffs
| Year | Team | Games | Car | Rush Yds | Rush TD | 1st Down | Y/C |
|---|---|---|---|---|---|---|---|
| 2005 | SF | 14 | 127 | 608 | 3 | 26 | 4.8 |
| 2006 | SF | 16 | 313 | 1695 | 8 | 68 | 5.4 |
| 2007 | SF | 15 | 260 | 1102 | 5 | 42 | 4.2 |
| 2008 | SF | 14 | 240 | 1036 | 6 | 45 | 4.3 |
| 2009 | SF | 14 | 229 | 1120 | 10 | 48 | 4.9 |
| 2010 | SF | 11 | 203 | 853 | 3 | 44 | 4.2 |
| 2011 | SF | 18 | 311 | 1374 | 8 | 65 | 4.4 |
| 2012 | SF | 19 | 321 | 1533 | 12 | 82 | 4.8 |
| 2013 | SF | 19 | 324 | 1292 | 10 | 63 | 4.0 |
| 2014 | SF | 16 | 255 | 1106 | 4 | 57 | 4.3 |
| 2015 | IND | 16 | 260 | 967 | 6 | 49 | 3.7 |
| 2016 | IND | 16 | 263 | 1025 | 4 | 50 | 3.9 |
| 2017 | IND | 16 | 261 | 961 | 3 | 50 | 3.7 |
| 2018 | MIA | 14 | 156 | 722 | 0 | 25 | 4.6 |
| 2019 | BUF | 16 | 174 | 621 | 2 | 35 | 3.6 |
| 2020 | NYJ | 15 | 187 | 653 | 2 | 33 | 3.5 |