Regular season
| Year | Team | Games | Att | Cmp | Cmp% | Pass Yds | Pass TD | INT | Sacks | Y/A | Rating |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1999 | SF | 13 | 375 | 225 | 60.0 | 2544 | 11 | 11 | 15 | 6.8 | 77.9 |
| 2000 | SF | 16 | 561 | 355 | 63.3 | 4278 | 31 | 10 | 24 | 7.6 | 97.6 |
| 2001 | SF | 16 | 504 | 316 | 62.7 | 3538 | 32 | 12 | 26 | 7.0 | 94.8 |
| 2002 | SF | 16 | 528 | 328 | 62.1 | 3344 | 21 | 10 | 17 | 6.3 | 85.6 |
| 2003 | SF | 13 | 392 | 225 | 57.4 | 2704 | 18 | 13 | 22 | 6.9 | 80.1 |
| 2004 | CLE | 11 | 252 | 144 | 57.1 | 1731 | 10 | 9 | 25 | 6.9 | 76.7 |
| 2005 | DET | 6 | 173 | 102 | 59.0 | 937 | 3 | 6 | 6 | 5.4 | 65.1 |
| 2006 | PHI | 8 | 188 | 116 | 61.7 | 1309 | 10 | 2 | 6 | 7.0 | 95.8 |
| 2007 | TB | 13 | 327 | 209 | 63.9 | 2440 | 13 | 4 | 19 | 7.5 | 94.6 |
| 2008 | TB | 12 | 377 | 244 | 64.7 | 2712 | 12 | 6 | 24 | 7.2 | 90.0 |