Regular season
| Year | Team | Games | Att | Cmp | Cmp% | Pass Yds | Pass TD | INT | Sacks | Y/A | Rating | Drop% | BadTh% | OnTgt% | Press% | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2014 | NE | 5 | 27 | 19 | 70.4 | 182 | 1 | 0 | 5 | 6.7 | 101.2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2015 | NE | 4 | 4 | 1 | 25.0 | 6 | 0 | 0 | 0 | 1.5 | 39.6 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2016 | NE | 6 | 63 | 43 | 68.3 | 502 | 4 | 0 | 3 | 8.0 | 113.3 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2017 | SF | 6 | 178 | 120 | 67.4 | 1560 | 7 | 5 | 8 | 8.8 | 96.2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2018 | SF | 3 | 89 | 53 | 59.6 | 718 | 5 | 3 | 13 | 8.1 | 90.0 | 5.7 | 18.4 | 0.0 | 30.8 | 2.4 |
| 2019 | SF | 16 | 476 | 329 | 69.1 | 3978 | 27 | 13 | 36 | 8.4 | 102.0 | 6.0 | 13.7 | 80.7 | 20.8 | 2.4 |
| 2020 | SF | 6 | 140 | 94 | 67.1 | 1096 | 7 | 5 | 11 | 7.8 | 92.4 | 6.4 | 17.1 | 77.9 | 21.3 | 2.3 |
| 2021 | SF | 15 | 441 | 301 | 68.3 | 3810 | 20 | 12 | 29 | 8.6 | 98.7 | 5.4 | 12.9 | 81.5 | 18.7 | 2.4 |
| 2022 | SF | 11 | 308 | 207 | 67.2 | 2437 | 16 | 4 | 18 | 7.9 | 103.0 | 6.9 | 12.7 | 74.5 | 15.5 | 2.3 |
| 2023 | LV | 7 | 169 | 110 | 65.1 | 1205 | 7 | 9 | 14 | 7.1 | 77.7 | 3.0 | 18.2 | 70.9 | 17.8 | 2.5 |
| 2024 | LA | 1 | 41 | 27 | 65.9 | 334 | 2 | 1 | 3 | 8.1 | 97.0 | 0.0 | 20.0 | 67.5 | 17.8 | 2.2 |