Regular season
| Year | Team | Games | Att | Cmp | Cmp% | Pass Yds | Pass TD | INT | Sacks | Y/A | Rating |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1998 | LAR | 1 | 11 | 4 | 36.4 | 39 | 0 | 0 | 0 | 3.5 | 47.2 |
| 1999 | LAR | 16 | 499 | 325 | 65.1 | 4353 | 41 | 13 | 29 | 8.7 | 109.2 |
| 2000 | STL | 11 | 347 | 235 | 67.7 | 3429 | 21 | 18 | 20 | 9.9 | 98.3 |
| 2001 | STL | 16 | 546 | 375 | 68.7 | 4830 | 36 | 22 | 38 | 8.8 | 101.4 |
| 2002 | STL | 7 | 220 | 144 | 65.5 | 1431 | 3 | 11 | 21 | 6.5 | 67.4 |
| 2003 | LA | 2 | 65 | 38 | 58.5 | 365 | 1 | 1 | 6 | 5.6 | 72.9 |
| 2004 | NYG | 10 | 277 | 174 | 62.8 | 2054 | 6 | 4 | 39 | 7.4 | 86.5 |
| 2005 | ARI | 10 | 375 | 242 | 64.5 | 2713 | 11 | 9 | 23 | 7.2 | 85.8 |
| 2006 | ARI | 6 | 168 | 108 | 64.3 | 1377 | 6 | 5 | 14 | 8.2 | 89.3 |
| 2007 | ARI | 14 | 452 | 282 | 62.4 | 3409 | 27 | 17 | 20 | 7.5 | 89.7 |
| 2008 | ARI | 16 | 599 | 402 | 67.1 | 4582 | 30 | 14 | 26 | 7.6 | 96.8 |
| 2009 | ARI | 15 | 514 | 340 | 66.1 | 3758 | 27 | 14 | 24 | 7.3 | 93.8 |