Regular season and playoffs
| Year | Team | Games | Att | Cmp | Cmp% | Pass Yds | Pass TD | INT | Sacks | Y/A | Rating |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1998 | LAR | 1 | 11 | 4 | 36.4 | 39 | 0 | 0 | 0 | 3.5 | 47.2 |
| 1999 | LAR | 16 | 499 | 325 | 65.1 | 4353 | 41 | 13 | 29 | 8.7 | 109.2 |
| 2000 | STL | 12 | 387 | 259 | 66.9 | 3794 | 24 | 21 | 22 | 9.8 | 96.8 |
| 2001 | STL | 19 | 653 | 443 | 67.8 | 5623 | 40 | 25 | 44 | 8.6 | 99.0 |
| 2002 | STL | 7 | 220 | 144 | 65.5 | 1431 | 3 | 11 | 21 | 6.5 | 67.4 |
| 2003 | LA | 2 | 65 | 38 | 58.5 | 365 | 1 | 1 | 6 | 5.6 | 72.9 |
| 2004 | NYG | 10 | 277 | 174 | 62.8 | 2054 | 6 | 4 | 39 | 7.4 | 86.5 |
| 2005 | ARI | 10 | 375 | 242 | 64.5 | 2713 | 11 | 9 | 23 | 7.2 | 85.8 |
| 2006 | ARI | 6 | 168 | 108 | 64.3 | 1377 | 6 | 5 | 14 | 8.2 | 89.3 |
| 2007 | ARI | 14 | 452 | 282 | 62.4 | 3409 | 27 | 17 | 20 | 7.5 | 89.7 |
| 2008 | ARI | 20 | 734 | 494 | 67.3 | 5729 | 41 | 17 | 31 | 7.8 | 99.7 |
| 2009 | ARI | 17 | 573 | 386 | 67.4 | 4342 | 32 | 15 | 26 | 7.6 | 97.5 |