Regular season
| Year | Team | Games | Att | Cmp | Cmp% | Pass Yds | Pass TD | INT | Sacks | Y/A | Rating | Drop% | BadTh% | OnTgt% | Press% | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2009 | DET | 10 | 377 | 201 | 53.3 | 2267 | 13 | 20 | 23 | 6.0 | 61.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2010 | DET | 3 | 96 | 57 | 59.4 | 535 | 6 | 1 | 4 | 5.6 | 91.3 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2011 | DET | 16 | 673 | 428 | 63.6 | 5100 | 41 | 16 | 38 | 7.6 | 97.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2012 | DET | 16 | 727 | 435 | 59.8 | 4967 | 20 | 17 | 29 | 6.8 | 79.8 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2013 | DET | 16 | 634 | 371 | 58.5 | 4650 | 29 | 19 | 23 | 7.3 | 84.2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2014 | DET | 16 | 602 | 363 | 60.3 | 4257 | 22 | 12 | 45 | 7.1 | 85.7 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2015 | DET | 16 | 592 | 398 | 67.2 | 4262 | 32 | 13 | 44 | 7.2 | 97.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2016 | DET | 16 | 594 | 388 | 65.3 | 4327 | 24 | 10 | 37 | 7.3 | 93.3 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2017 | DET | 16 | 565 | 371 | 65.7 | 4446 | 29 | 10 | 47 | 7.9 | 99.3 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2018 | DET | 16 | 555 | 367 | 66.1 | 3777 | 21 | 11 | 40 | 6.8 | 89.9 | 5.4 | 17.4 | 0.0 | 21.4 | 2.3 |
| 2019 | DET | 8 | 291 | 187 | 64.3 | 2499 | 19 | 5 | 18 | 8.6 | 106.0 | 3.2 | 20.8 | 70.8 | 19.1 | 2.4 |
| 2020 | DET | 16 | 528 | 339 | 64.2 | 4084 | 26 | 10 | 38 | 7.7 | 96.3 | 6.4 | 18.3 | 77.6 | 21.0 | 2.4 |
| 2021 | LA | 17 | 601 | 404 | 67.2 | 4886 | 41 | 17 | 30 | 8.1 | 102.9 | 5.2 | 18.6 | 76.6 | 16.3 | 2.5 |
| 2022 | LA | 9 | 303 | 206 | 68.0 | 2087 | 10 | 8 | 29 | 6.9 | 87.4 | 3.7 | 18.2 | 75.7 | 23.4 | 2.3 |
| 2023 | LA | 15 | 521 | 326 | 62.6 | 3965 | 24 | 11 | 30 | 7.6 | 92.5 | 6.7 | 19.0 | 75.0 | 17.7 | 2.5 |
| 2024 | LA | 16 | 517 | 340 | 65.8 | 3762 | 20 | 8 | 28 | 7.3 | 93.7 | 3.0 | 17.6 | 74.3 | 22.3 | 2.4 |
| 2025 | LA | 17 | 597 | 388 | 65.0 | 4707 | 46 | 8 | 23 | 7.9 | 109.2 | 4.8 | 18.1 | 73.6 | 18.5 | 2.4 |
| 2026 | LA | 7 | 278 | 187 | 67.3 | 1989 | 14 | 7 | 11 | 7.2 | 94.2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |