Regular season
| Year | Team | Games | Att | Cmp | Cmp% | Pass Yds | Pass TD | INT | Sacks | Y/A | Rating | Drop% | BadTh% | OnTgt% | Press% | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2011 | BAL | 2 | 1 | 1 | 100.0 | 18 | 0 | 0 | 2 | 18.0 | 118.8 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2012 | BAL | 5 | 29 | 17 | 58.6 | 179 | 0 | 1 | 3 | 6.2 | 62.3 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2013 | BAL | 3 | 5 | 1 | 20.0 | 2 | 0 | 1 | 0 | 0.4 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2015 | BUF | 14 | 380 | 242 | 63.7 | 3035 | 20 | 6 | 36 | 8.0 | 99.4 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2016 | BUF | 15 | 436 | 269 | 61.7 | 3023 | 17 | 6 | 42 | 6.9 | 89.7 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2017 | BUF | 15 | 420 | 263 | 62.6 | 2799 | 14 | 4 | 46 | 6.7 | 89.2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 2018 | CLE | 4 | 85 | 42 | 49.4 | 473 | 2 | 2 | 13 | 5.6 | 64.5 | 6.3 | 24.1 | 0.0 | 39.4 | 2.4 |
| 2019 | LAC | 4 | 6 | 4 | 66.7 | 33 | 1 | 0 | 0 | 5.5 | 120.1 | 16.7 | 16.7 | 83.3 | 0.0 | 2.1 |
| 2020 | LAC | 2 | 30 | 16 | 53.3 | 208 | 0 | 0 | 2 | 6.9 | 75.4 | 3.6 | 21.4 | 71.4 | 26.5 | 2.5 |
| 2021 | HOU | 6 | 150 | 91 | 60.7 | 966 | 5 | 5 | 13 | 6.4 | 76.7 | 3.4 | 22.1 | 69.0 | 27.0 | 2.3 |
| 2022 | NYG | 2 | 8 | 6 | 75.0 | 58 | 1 | 1 | 3 | 7.2 | 94.8 | 12.5 | 0.0 | 87.5 | 26.7 | 2.6 |
| 2023 | NYG | 10 | 180 | 116 | 64.4 | 1341 | 5 | 3 | 17 | 7.4 | 89.1 | 6.6 | 14.5 | 80.7 | 22.8 | 2.3 |
| 2024 | NYJ | 2 | 22 | 17 | 77.3 | 119 | 3 | 0 | 0 | 5.4 | 128.6 | 4.8 | 9.5 | 90.5 | 20.8 | 2.0 |
| 2025 | NYJ | 6 | 134 | 80 | 59.7 | 779 | 5 | 5 | 14 | 5.8 | 72.9 | 9.5 | 13.5 | 73.0 | 26.5 | 2.4 |