Franchise 57 seasons 437–443–2 all-time 21 playoff trips 0 Super Bowls
1994 players
Passing
| Jim Kelly | 448 | 285 | 3,114 | 22 | 17 | 7.0 |
| Frank Reich | 93 | 56 | 568 | 1 | 4 | 6.1 |
| Andre Reed | 1 | 1 | 32 | 0 | 0 | 32.0 |
Rushing
| Thurman Thomas | 287 | 1,093 | 7 | 3.8 |
| Kenneth Davis | 91 | 381 | 2 | 4.2 |
| Carwell Gardner | 41 | 135 | 4 | 3.3 |
| Andre Reed | 10 | 87 | 0 | 8.7 |
| Jim Kelly | 25 | 77 | 1 | 3.1 |
| Yonel Jourdain | 17 | 56 | 0 | 3.3 |
| Don Beebe | 2 | 11 | 0 | 5.5 |
| Nate Turner | 2 | 4 | 0 | 2.0 |
| Frank Reich | 6 | 3 | 0 | 0.5 |
| Russell Copeland | 1 | -7 | 0 | -7.0 |
| Chris Mohr | 1 | -9 | 0 | -9.0 |
Receiving
| Andre Reed | 145 | 90 | 1,303 | 8 | 9.0 |
| Don Beebe | 74 | 40 | 527 | 4 | 7.1 |
| Bill Brooks | 63 | 42 | 482 | 2 | 7.7 |
| Pete Metzelaars | 68 | 49 | 428 | 5 | 6.3 |
| Thurman Thomas | 71 | 50 | 349 | 2 | 4.9 |
| Russell Copeland | 39 | 21 | 255 | 1 | 6.5 |
| Carwell Gardner | 14 | 11 | 89 | 0 | 6.4 |
| Kenneth Davis | 23 | 18 | 82 | 0 | 3.6 |
| Yonel Jourdain | 10 | 10 | 56 | 0 | 5.6 |
| Vince Marrow | 7 | 5 | 44 | 0 | 6.3 |
| Lonnie Johnson | 4 | 3 | 42 | 0 | 10.5 |
| Damon Thomas | 2 | 2 | 31 | 0 | 15.5 |
| Nate Turner | 1 | 1 | 26 | 1 | 26.0 |
Defense
| Darryl Talley | ROLB | 115 | 82 | 0.0 | 0 | 1 |
| Marvcus Patton | LILB | 95 | 62 | 0.0 | 2 | 0 |
| Bruce Smith | RDE | 81 | 57 | 10.0 | 1 | 5 |
| Henry Jones | SS | 81 | 61 | 1.0 | 2 | 1 |
| Matt Darby | FS | 81 | 52 | 0.0 | 4 | 0 |
| Mark Maddox | RILB | 78 | 52 | 0.0 | 1 | 1 |
| Mickey Washington | LCB | 77 | 65 | 0.5 | 3 | 1 |
| Cornelius Bennett | LOLB | 77 | 58 | 5.0 | 0 | 1 |
| Phil Hansen | LDE | 71 | 55 | 5.5 | 0 | 2 |
| Thomas Smith | RCB | 48 | 41 | 0.0 | 1 | 1 |
| Jeff Wright | NT | 30 | 19 | 2.0 | 0 | 0 |
| Kurt Schulz | DB | 23 | 13 | 0.0 | 0 | 0 |
| Keith Goganious | LB | 21 | 16 | 0.0 | 0 | 0 |
| Oliver Barnett | DE | 19 | 14 | 1.0 | 0 | 0 |
| Mike Lodish | NT | 17 | 11 | 0.0 | 0 | 0 |
| Jeff Burris | DB | 16 | 13 | 0.0 | 2 | 0 |
| James Patton | LB | 3 | 3 | 0.0 | 0 | 0 |
| Ed Philion | DT | 3 | 2 | 0.0 | 0 | 0 |
| Sam Rogers | LB | 3 | 0 | 0.0 | 0 | 0 |
| Jerome Henderson | DB | 2 | 2 | 0.0 | 0 | 0 |
| Marlo Perry | LB | 1 | 1 | 0.0 | 0 | 0 |