Franchise 57 seasons 437–443–2 all-time 21 playoff trips 0 Super Bowls
2020 players
Passing
| Josh Allen | 572 | 396 | 4,544 | 37 | 10 | 7.9 |
| Matt Barkley | 21 | 11 | 197 | 1 | 1 | 9.4 |
| Cole Beasley | 1 | 1 | 20 | 1 | 0 | 20.0 |
| Jaquan Johnson | 1 | 1 | 13 | 0 | 0 | 13.0 |
| Isaiah McKenzie | 1 | 1 | 12 | 1 | 0 | 12.0 |
Rushing
| Devin Singletary | 156 | 687 | 2 | 4.4 |
| Zack Moss | 112 | 481 | 4 | 4.3 |
| Josh Allen | 102 | 421 | 8 | 4.1 |
| T.J. Yeldon | 10 | 70 | 0 | 7.0 |
| Antonio Williams | 12 | 63 | 2 | 5.2 |
| Isaiah McKenzie | 10 | 9 | 0 | 0.9 |
| Stefon Diggs | 1 | 1 | 0 | 1.0 |
| Gabe Davis | 1 | 0 | 0 | 0.0 |
| Andre Roberts | 1 | -3 | 0 | -3.0 |
| Matt Barkley | 6 | -6 | 0 | -1.0 |
Receiving
| Stefon Diggs | 166 | 127 | 1,535 | 8 | 9.2 |
| Cole Beasley | 107 | 82 | 967 | 4 | 9.0 |
| Gabe Davis | 62 | 35 | 599 | 7 | 9.7 |
| John Brown | 52 | 33 | 458 | 3 | 8.8 |
| Dawson Knox | 44 | 24 | 288 | 3 | 6.5 |
| Isaiah McKenzie | 34 | 30 | 282 | 5 | 8.3 |
| Devin Singletary | 50 | 38 | 269 | 0 | 5.4 |
| Tyler Kroft | 16 | 12 | 119 | 3 | 7.4 |
| Zack Moss | 18 | 14 | 95 | 1 | 5.3 |
| Lee Smith | 6 | 4 | 35 | 2 | 5.8 |
| Andre Roberts | 5 | 4 | 34 | 0 | 6.8 |
| Jake Kumerow | 1 | 1 | 22 | 1 | 22.0 |
| T.J. Yeldon | 4 | 1 | 22 | 1 | 5.5 |
| Antonio Williams | 1 | 1 | 20 | 0 | 20.0 |
| Reggie Gilliam | 2 | 2 | 16 | 1 | 8.0 |
| Siran Neal | 1 | 1 | 13 | 0 | 13.0 |
| Josh Allen | 1 | 1 | 12 | 1 | 12.0 |
Defense
| Tremaine Edmunds | MLB | 115 | 73 | 2.0 | 0 | 3 | 0 |
| Jordan Poyer | FS | 111 | 78 | 2.0 | 2 | 5 | 2 |
| Taron Johnson | CB | 86 | 62 | 1.0 | 1 | 7 | 1 |
| Micah Hyde | S | 67 | 45 | 0.0 | 1 | 5 | 0 |
| A.J. Klein | OLB | 65 | 43 | 5.0 | 0 | 4 | 2 |
| Tre'Davious White | CB | 54 | 41 | 1.5 | 3 | 11 | 1 |
| Levi Wallace | DB | 45 | 31 | 0.0 | 2 | 8 | 0 |
| Matt Milano | OLB | 40 | 30 | 3.5 | 1 | 3 | 0 |
| Ed Oliver | DT | 30 | 20 | 3.0 | 0 | 3 | 1 |
| Mario Addison | DL | 27 | 18 | 5.0 | 0 | 4 | 0 |
| Jerry Hughes | DE | 26 | 16 | 4.5 | 1 | 3 | 2 |
| Tyler Matakevich | ILB | 23 | 12 | 0.0 | 0 | 2 | 0 |
| Quinton Jefferson | DE | 21 | 12 | 3.0 | 0 | 1 | 1 |
| Justin Zimmer | DT | 19 | 11 | 1.0 | 0 | 0 | 1 |
| Tyrel Dodson | LB | 18 | 9 | 1.0 | 0 | 2 | 0 |
| Dean Marlowe | S | 17 | 11 | 1.5 | 2 | 3 | 0 |
| Josh Norman | CB | 17 | 14 | 0.0 | 1 | 4 | 1 |
| Harrison Phillips | DT | 17 | 10 | 0.0 | 0 | 0 | 0 |
| Vernon Butler | DT | 16 | 7 | 0.0 | 0 | 1 | 1 |
| Dane Jackson | CB | 15 | 13 | 0.0 | 1 | 5 | 0 |
| Trent Murphy | DE | 15 | 11 | 2.0 | 0 | 0 | 0 |
| Darryl Johnson | OLB | 12 | 9 | 1.0 | 0 | 0 | 0 |
| A.J. Epenesa | DE | 12 | 9 | 1.0 | 0 | 1 | 0 |
| Siran Neal | CB | 11 | 7 | 0.0 | 0 | 1 | 0 |
| Andre Smith | LB | 9 | 8 | 0.0 | 0 | 0 | 1 |
| Cam Lewis | CB | 6 | 4 | 0.0 | 0 | 0 | 0 |
| Gabe Davis | WR | 4 | 4 | 0.0 | 0 | 0 | 0 |
| Taiwan Jones | RB | 4 | 3 | 0.0 | 0 | 0 | 0 |
| Jaquan Johnson | DB | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Reggie Gilliam | FB | 2 | 2 | 0.0 | 0 | 0 | 1 |
| Daryl Williams | OT | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Jon Feliciano | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Stefon Diggs | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Deon Lacey | LB | 1 | 0 | 0.0 | 0 | 0 | 0 |
| Brian Winters | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Cole Beasley | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Tyler Kroft | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Reid Ferguson | LS | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Isaiah McKenzie | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Mike Love | DE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Dion Dawkins | OT | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Darron Lee | ILB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Corey Bojorquez | P | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Devin Singletary | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Josh Allen | QB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Tyler Bass | K | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Josh Thomas | DB | 1 | 1 | 0.0 | 0 | 0 | 0 |