Franchise 76 seasons 584–547–10 all-time 29 playoff trips 2 Super Bowls
2010 players
Passing
| Peyton Manning | 679 | 450 | 4,700 | 33 | 17 | 6.9 |
Rushing
| Donald Brown | 129 | 497 | 2 | 3.9 |
| Joseph Addai | 116 | 495 | 4 | 4.3 |
| Mike Hart | 43 | 185 | 1 | 4.3 |
| Dominic Rhodes | 37 | 172 | 0 | 4.6 |
| Javarris James | 46 | 112 | 6 | 2.4 |
| Peyton Manning | 18 | 18 | 0 | 1.0 |
| Pierre Garcon | 2 | 6 | 0 | 3.0 |
| Devin Moore | 2 | -2 | 0 | -1.0 |
Receiving
| Reggie Wayne | 175 | 111 | 1,355 | 6 | 7.7 |
| Pierre Garcon | 120 | 68 | 816 | 6 | 6.8 |
| Jacob Tamme | 93 | 67 | 631 | 4 | 6.8 |
| Austin Collie | 70 | 57 | 617 | 8 | 8.8 |
| Blair White | 57 | 36 | 355 | 5 | 6.2 |
| Dallas Clark | 53 | 37 | 347 | 3 | 6.5 |
| Donald Brown | 28 | 20 | 205 | 0 | 7.3 |
| Joseph Addai | 26 | 19 | 124 | 0 | 4.8 |
| Anthony Gonzalez | 9 | 5 | 67 | 0 | 7.4 |
| Javarris James | 11 | 9 | 63 | 0 | 5.7 |
| Brandon James | 11 | 6 | 40 | 0 | 3.6 |
| Brody Eldridge | 9 | 5 | 39 | 0 | 4.3 |
| Mike Hart | 6 | 6 | 25 | 0 | 4.2 |
| Gijon Robinson | 7 | 3 | 12 | 1 | 1.7 |
| Dominic Rhodes | 4 | 1 | 4 | 0 | 1.0 |
Defense
| Antoine Bethea | FS | 89 | 60 | 0.5 | 1 | 5 | 1 |
| Pat Angerer | ILB | 68 | 38 | 1.0 | 0 | 2 | 1 |
| Gary Brackett | MLB | 58 | 37 | 0.5 | 0 | 3 | 0 |
| Jacob Lacey | DB | 57 | 44 | 0.0 | 1 | 2 | 0 |
| Kelvin Hayden | DB | 56 | 38 | 0.0 | 2 | 8 | 1 |
| Jerraud Powers | DB | 49 | 38 | 0.0 | 2 | 9 | 0 |
| Philip Wheeler | OLB | 48 | 27 | 0.0 | 0 | 1 | 0 |
| Tyjuan Hagler | OLB | 47 | 36 | 1.0 | 1 | 3 | 0 |
| Robert Mathis | OLB | 46 | 30 | 11.0 | 0 | 1 | 1 |
| Kavell Conner | OLB | 46 | 25 | 0.0 | 0 | 0 | 1 |
| Aaron Francisco | S | 44 | 30 | 0.0 | 2 | 3 | 0 |
| Justin Tryon | DB | 39 | 29 | 0.0 | 0 | 7 | 0 |
| Daniel Muir | DT | 29 | 20 | 0.0 | 0 | 0 | 0 |
| Clint Session | LB | 28 | 21 | 1.0 | 0 | 1 | 0 |
| Dwight Freeney | DE | 25 | 21 | 10.0 | 0 | 2 | 5 |
| Keyunta Dawson | DE | 24 | 12 | 0.0 | 0 | 1 | 0 |
| Eric Foster | DT | 23 | 15 | 3.5 | 0 | 1 | 0 |
| Cornelius Brown | DB | 22 | 17 | 0.0 | 0 | 3 | 0 |
| Antonio Johnson | DT | 19 | 13 | 0.5 | 0 | 0 | 0 |
| Fili Moala | DE | 18 | 12 | 0.0 | 0 | 1 | 0 |
| Melvin Bullitt | S | 12 | 9 | 0.0 | 1 | 1 | 0 |
| Cody Glenn | LB | 11 | 8 | 0.0 | 0 | 0 | 0 |
| Deshea Townsend | DB | 9 | 8 | 0.0 | 0 | 1 | 0 |
| Jacob Tamme | TE | 6 | 5 | 0.0 | 0 | 0 | 0 |
| Mike Newton | DB | 5 | 3 | 0.0 | 0 | 0 | 0 |
| Blair White | WR | 5 | 5 | 0.0 | 0 | 0 | 0 |
| Nate Triplett | LB | 4 | 4 | 0.0 | 0 | 0 | 0 |
| Taj Smith | WR | 4 | 3 | 0.0 | 0 | 0 | 1 |
| Jerry Hughes | DE | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Pierre Garcon | WR | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Al Afalava | S | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Ken Hamlin | DB | 3 | 1 | 0.0 | 1 | 1 | 0 |
| Brody Eldridge | TE | 2 | 2 | 0.0 | 0 | 0 | 1 |
| Patrick McAfee | P | 2 | 1 | 0.0 | 0 | 0 | 0 |
| Mitch King | DT | 2 | 0 | 0.0 | 0 | 0 | 0 |
| Mike Richardson | DB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Reggie Wayne | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Dallas Clark | TE | 1 | 0 | 0.0 | 0 | 0 | 0 |
| Ryan Diem | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Charlie Johnson | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Mike Pollak | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| DaJuan Morgan | DB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Donald Brown | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Devin Moore | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Mike Hart | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jaimie Thomas | G | 1 | 0 | 0.0 | 0 | 0 | 0 |
| Brandon King | DB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| David Pender | CB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Joique Bell | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Ricardo Mathews | DE | 1 | 0 | 0.0 | 0 | 0 | 0 |