Franchise 57 seasons 446–445–6 all-time 20 playoff trips 3 Super Bowls
2002 players
Passing
| Rich Gannon | 618 | 418 | 4,689 | 26 | 10 | 7.6 |
| Terry Kirby | 1 | 0 | 0 | 0 | 0 | 0.0 |
Rushing
| Charlie Garner | 182 | 962 | 7 | 5.3 |
| Tyrone Wheatley | 108 | 419 | 2 | 3.9 |
| Rich Gannon | 50 | 156 | 3 | 3.1 |
| Zack Crockett | 40 | 118 | 8 | 3.0 |
| Terry Kirby | 16 | 51 | 0 | 3.2 |
| Jerry Rice | 3 | 20 | 0 | 6.7 |
| Tim Brown | 6 | 19 | 0 | 3.2 |
| Randy Jordan | 3 | 14 | 1 | 4.7 |
| Jerry Porter | 4 | 6 | 0 | 1.5 |
| Marques Tuiasosopo | 2 | -3 | 0 | -1.5 |
Receiving
| Jerry Rice | 150 | 92 | 1,211 | 7 | 8.1 |
| Charlie Garner | 111 | 91 | 941 | 4 | 8.5 |
| Tim Brown | 127 | 81 | 930 | 2 | 7.3 |
| Jerry Porter | 70 | 51 | 688 | 9 | 9.8 |
| Doug Jolley | 37 | 32 | 409 | 2 | 11.1 |
| Roland Williams | 40 | 27 | 213 | 0 | 5.3 |
| Terry Kirby | 22 | 17 | 115 | 1 | 5.2 |
| Tyrone Wheatley | 20 | 12 | 71 | 0 | 3.6 |
| Jon Ritchie | 21 | 10 | 66 | 1 | 3.1 |
| Marcus Knight | 5 | 3 | 26 | 0 | 5.2 |
| Randy Jordan | 4 | 2 | 19 | 0 | 4.8 |
Defense
| Eric Barton | ILB | 105 | 75 | 6.0 | 2 | 4 | 3 |
| Bill Romanowski | OLB | 77 | 51 | 4.0 | 1 | 5 | 0 |
| Rod Woodson | FS | 73 | 61 | 0.0 | 8 | 16 | 0 |
| Napoleon Harris | MLB | 64 | 42 | 0.5 | 0 | 2 | 0 |
| Derrick Gibson | DB | 56 | 42 | 0.0 | 0 | 6 | 0 |
| Travian Smith | OLB | 44 | 36 | 5.0 | 0 | 2 | 0 |
| Tory James | CB | 37 | 33 | 0.0 | 4 | 19 | 0 |
| Anthony Dorsett | FS | 34 | 23 | 0.0 | 0 | 4 | 0 |
| John Parrella | DT | 32 | 24 | 1.0 | 0 | 4 | 1 |
| Terrance Shaw | CB | 31 | 25 | 0.0 | 2 | 10 | 0 |
| Charles Woodson | FS | 31 | 29 | 0.0 | 1 | 4 | 4 |
| Rod Coleman | DT | 30 | 24 | 11.0 | 0 | 3 | 0 |
| Tony Bryant | DE | 25 | 17 | 2.5 | 0 | 2 | 1 |
| DeLawrence Grant | LB | 23 | 18 | 3.0 | 0 | 0 | 0 |
| Clarence Love | CB | 19 | 17 | 0.0 | 0 | 4 | 0 |
| Trace Armstrong | DE | 19 | 14 | 4.0 | 1 | 2 | 1 |
| Phillip Buchanon | DB | 18 | 18 | 0.0 | 2 | 5 | 0 |
| Sam Adams | DT | 18 | 14 | 2.0 | 0 | 2 | 0 |
| Chris Cooper | DE | 16 | 11 | 1.0 | 0 | 1 | 1 |
| Brandon Jennings | DB | 13 | 12 | 0.0 | 0 | 2 | 0 |
| Marcus Williams | TE | 9 | 8 | 0.0 | 0 | 0 | 0 |
| Marcus Knight | WR | 7 | 5 | 0.0 | 0 | 0 | 0 |
| Zack Crockett | RB | 7 | 6 | 0.0 | 0 | 0 | 0 |
| Tim Johnson | LB | 6 | 4 | 0.0 | 0 | 0 | 0 |
| Eric Johnson | LB | 6 | 5 | 0.0 | 0 | 0 | 0 |
| Randy Jordan | RB | 4 | 3 | 0.0 | 0 | 0 | 0 |
| Jerry Porter | WR | 4 | 4 | 0.0 | 0 | 0 | 0 |
| Alvis Whitted | WR | 4 | 4 | 0.0 | 0 | 0 | 0 |
| Jerry Rice | WR | 4 | 4 | 0.0 | 0 | 0 | 0 |
| Shane Lechler | P | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Regan Upshaw | DE | 3 | 2 | 2.0 | 0 | 0 | 0 |
| Junior Ioane | DE | 3 | 2 | 1.0 | 0 | 0 | 0 |
| Sebastian Janikowski | K | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Jon Ritchie | FB | 3 | 3 | 0.0 | 0 | 0 | 0 |
| Lincoln Kennedy | OT | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Rich Gannon | QB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Charlie Garner | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Terry Kirby | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Roland Williams | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Adam Treu | C | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Frank Middleton | G | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Barry Sims | OT | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Mondriel Fulcher | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Derek Combs | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Doug Jolley | TE | 1 | 1 | 0.0 | 0 | 0 | 0 |