Franchise 77 seasons 609–519–14 all-time 30 playoff trips 5 Super Bowls
1981 players
Passing
| Joe Montana | 488 | 311 | 3,565 | 19 | 12 | 7.3 |
| Guy Benjamin | 26 | 15 | 171 | 1 | 1 | 6.6 |
| Freddie Solomon | 1 | 1 | 25 | 0 | 0 | 25.0 |
| Walt Easley | 1 | 1 | 5 | 0 | 0 | 5.0 |
| Dwight Clark | 1 | 0 | 0 | 0 | 0 | 0.0 |
Rushing
| Ricky Patton | 152 | 543 | 4 | 3.6 |
| Earl Cooper | 98 | 330 | 1 | 3.4 |
| Johnny Davis | 94 | 297 | 7 | 3.2 |
| Walt Easley | 76 | 224 | 1 | 2.9 |
| Paul Hofer | 60 | 193 | 1 | 3.2 |
| Bill Ring | 22 | 106 | 0 | 4.8 |
| Joe Montana | 25 | 95 | 2 | 3.8 |
| Amos Lawrence | 13 | 48 | 1 | 3.7 |
| Freddie Solomon | 9 | 43 | 0 | 4.8 |
| Dwight Clark | 3 | 32 | 0 | 10.7 |
| Lenvil Elliott | 7 | 29 | 0 | 4.1 |
| Guy Benjamin | 1 | 1 | 0 | 1.0 |
Receiving
| Dwight Clark | 122 | 85 | 1,105 | 4 | 9.1 |
| Freddie Solomon | 112 | 59 | 969 | 8 | 8.7 |
| Earl Cooper | 71 | 51 | 477 | 0 | 6.7 |
| Charle Young | 52 | 37 | 400 | 5 | 7.7 |
| Paul Hofer | 34 | 27 | 244 | 0 | 7.2 |
| Ricky Patton | 42 | 27 | 195 | 1 | 4.6 |
| Mike Wilson | 11 | 9 | 125 | 1 | 11.4 |
| Lenvil Elliott | 11 | 7 | 81 | 0 | 7.4 |
| Walt Easley | 12 | 9 | 62 | 0 | 5.2 |
| Eason Ramson | 7 | 4 | 45 | 0 | 6.4 |
| Bill Ring | 4 | 3 | 28 | 1 | 7.0 |
| Mike Shumann | 7 | 3 | 21 | 0 | 3.0 |
| Amos Lawrence | 5 | 3 | 10 | 0 | 2.0 |
| Brian Peets | 1 | 1 | 5 | 0 | 5.0 |
| Johnny Davis | 5 | 3 | -1 | 0 | -0.2 |
Defense
| Ronnie Lott | LCB | 89 | 89 | 0.0 | 7 | 5 |
| Dwaine Board | RDE | 0 | 0 | 7.0 | 0 | 1 |
| Fred Dean | DE | 0 | 0 | 13.0 | 0 | 0 |
| Willie Harper | LOLB | 0 | 0 | 1.0 | 0 | 2 |
| John Harty | NT | 0 | 0 | 0.5 | 0 | 0 |
| Pete Kugler | DE | 0 | 0 | 1.0 | 0 | 1 |
| Bobby Leopold | LB | 0 | 0 | 0.5 | 0 | 1 |
| Milt McColl | LB | 0 | 0 | 1.0 | 1 | 0 |
| Lawrence Pillers | RDE | 0 | 0 | 7.0 | 0 | 1 |
| Archie Reese | NT | 0 | 0 | 0.5 | 0 | 0 |
| Jim Stuckey | LDE | 0 | 0 | 2.5 | 0 | 0 |
| Keena Turner | ROLB | 0 | 0 | 3.0 | 1 | 0 |