Franchise 77 seasons 609–519–14 all-time 30 playoff trips 5 Super Bowls
2002 players
Passing
| Jeff Garcia | 528 | 328 | 3,344 | 21 | 10 | 6.3 |
| Tim Rattay | 43 | 26 | 232 | 2 | 0 | 5.4 |
Rushing
| Garrison Hearst | 215 | 972 | 8 | 4.5 |
| Kevan Barlow | 145 | 675 | 4 | 4.7 |
| Jeff Garcia | 73 | 353 | 3 | 4.8 |
| Paul Smith | 18 | 90 | 0 | 5.0 |
| Terrell Owens | 7 | 79 | 1 | 11.3 |
| Fred Beasley | 26 | 75 | 0 | 2.9 |
| Tim Rattay | 5 | 0 | 0 | 0.0 |
Receiving
| Terrell Owens | 159 | 100 | 1,300 | 13 | 8.2 |
| Tai Streets | 109 | 72 | 756 | 5 | 6.9 |
| J.J. Stokes | 55 | 32 | 332 | 1 | 6.0 |
| Eric Johnson | 65 | 36 | 321 | 0 | 4.9 |
| Garrison Hearst | 69 | 48 | 317 | 1 | 4.6 |
| Cedrick Wilson | 22 | 15 | 166 | 1 | 7.5 |
| Fred Beasley | 32 | 22 | 152 | 1 | 4.8 |
| Kevan Barlow | 21 | 14 | 136 | 1 | 6.5 |
| Justin Swift | 15 | 10 | 63 | 0 | 4.2 |
| Paul Smith | 8 | 5 | 33 | 0 | 4.1 |
Defense
| Derek M. Smith | ILB | 88 | 59 | 1.0 | 0 | 6 | 1 |
| Jason Webster | DB | 76 | 62 | 0.0 | 1 | 11 | 0 |
| Julian Peterson | OLB | 73 | 55 | 2.0 | 1 | 7 | 2 |
| Tony Parrish | S | 58 | 49 | 0.0 | 7 | 17 | 1 |
| Jeff Ulbrich | ILB | 55 | 32 | 1.5 | 0 | 0 | 1 |
| Ahmed Plummer | CB | 54 | 43 | 0.0 | 1 | 18 | 1 |
| Andre Carter | DE | 46 | 37 | 12.5 | 0 | 4 | 3 |
| Ronnie Heard | FS | 40 | 32 | 0.0 | 4 | 5 | 0 |
| Mike Rumph | DB | 38 | 33 | 0.0 | 0 | 7 | 1 |
| Chike Okeafor | OLB | 36 | 25 | 6.0 | 0 | 4 | 2 |
| Dana Stubblefield | DT | 30 | 21 | 3.0 | 0 | 1 | 1 |
| Rashad Holman | CB | 24 | 22 | 0.0 | 1 | 1 | 0 |
| Jamie Winborn | OLB | 24 | 18 | 1.0 | 0 | 2 | 0 |
| Bryant Young | DT | 22 | 14 | 2.0 | 0 | 0 | 0 |
| Zack Bronson | DB | 17 | 12 | 0.0 | 3 | 3 | 1 |
| John Keith | DB | 17 | 11 | 0.0 | 0 | 1 | 0 |
| Brandon Moore | LB | 17 | 14 | 0.0 | 0 | 2 | 1 |
| Quincy Stewart | LB | 15 | 12 | 0.0 | 1 | 1 | 0 |
| Sean Moran | DE | 13 | 9 | 0.0 | 0 | 0 | 0 |
| Jimmy Williams | DB | 12 | 10 | 0.0 | 0 | 0 | 0 |
| Jim Flanigan | DT | 10 | 5 | 1.0 | 0 | 0 | 0 |
| John Engelberger | DE | 9 | 8 | 0.0 | 0 | 0 | 0 |
| Jason Moore | DB | 9 | 8 | 0.0 | 0 | 0 | 0 |
| Paul Smith | RB | 8 | 8 | 0.0 | 0 | 0 | 0 |
| Tai Streets | WR | 7 | 7 | 0.0 | 0 | 0 | 0 |
| Saleem Rasheed | LB | 6 | 5 | 1.0 | 0 | 0 | 0 |
| Cornelius Anthony | LB | 6 | 5 | 0.0 | 0 | 0 | 0 |
| Frank Strong | DB | 5 | 5 | 0.0 | 0 | 0 | 0 |
| Josh Shaw | DT | 3 | 3 | 1.0 | 0 | 0 | 0 |
| Terry Jackson | RB | 3 | 2 | 0.0 | 0 | 0 | 0 |
| Brian Jennings | LS | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Tim Hauck | DB | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Fred Beasley | FB | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Cedrick Wilson | WR | 2 | 2 | 0.0 | 0 | 0 | 0 |
| James Jordan | WR | 2 | 2 | 0.0 | 0 | 0 | 0 |
| Jeremy Newberry | C | 1 | 0 | 0.0 | 0 | 0 | 0 |
| Scott Gragg | OT | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Justin Swift | WR | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jamal Robertson | RB | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Jeff Chandler | K | 1 | 1 | 0.0 | 0 | 0 | 0 |
| Kyle Kosier | G | 1 | 1 | 0.0 | 0 | 0 | 0 |