Franchise 77 seasons 609–519–14 all-time 30 playoff trips 5 Super Bowls
1991 players
Passing
| Steve Young | 279 | 180 | 2,517 | 17 | 8 | 9.0 |
| Steve Bono | 237 | 141 | 1,617 | 11 | 4 | 6.8 |
| Bill Musgrave | 5 | 4 | 33 | 1 | 0 | 6.6 |
| Harry Sydney | 1 | 0 | 0 | 0 | 0 | 0.0 |
Rushing
| Keith Henderson | 137 | 561 | 2 | 4.1 |
| Steve Young | 66 | 415 | 4 | 6.3 |
| Dexter Carter | 85 | 379 | 2 | 4.5 |
| Harry Sydney | 57 | 245 | 5 | 4.3 |
| Tom Rathman | 63 | 183 | 6 | 2.9 |
| Steve Bono | 17 | 46 | 0 | 2.7 |
| Spencer Tillman | 13 | 40 | 0 | 3.1 |
| Jerry Rice | 1 | 2 | 0 | 2.0 |
| Joe Prokop | 1 | -10 | 0 | -10.0 |
Receiving
| Jerry Rice | 134 | 80 | 1,206 | 14 | 9.0 |
| John Taylor | 109 | 64 | 1,011 | 9 | 9.3 |
| Brent Jones | 51 | 27 | 417 | 0 | 8.2 |
| Keith Henderson | 37 | 30 | 303 | 0 | 8.2 |
| Mike Sherrard | 39 | 24 | 296 | 2 | 7.6 |
| Tom Rathman | 44 | 34 | 286 | 0 | 6.5 |
| Dexter Carter | 33 | 23 | 253 | 1 | 7.7 |
| Jamie Williams | 32 | 22 | 235 | 1 | 7.3 |
| Harry Sydney | 16 | 13 | 90 | 2 | 5.6 |
| Sanjay Beach | 6 | 4 | 43 | 0 | 7.2 |
| Wesley Walls | 3 | 2 | 24 | 0 | 8.0 |
| Spencer Tillman | 3 | 2 | 3 | 0 | 1.0 |
Defense
| Dave Whitmore | DB | 83 | 83 | 1.0 | 1 | 0 |
| Bill Romanowski | ROLB | 76 | 76 | 1.0 | 1 | 0 |
| Don Griffin | RCB | 57 | 57 | 0.0 | 1 | 1 |
| Charles Haley | LOLB | 53 | 53 | 7.0 | 0 | 2 |
| Pierce Holt | LDE | 44 | 44 | 3.0 | 0 | 0 |
| Dennis Brown | DE | 38 | 38 | 3.0 | 0 | 2 |
| Merton Hanks | LCB | 37 | 37 | 0.0 | 0 | 1 |
| Tim Harris | LB | 34 | 34 | 3.0 | 0 | 1 |
| Ted Washington | NT | 21 | 21 | 1.0 | 0 | 0 |
| Antonio Goss | LB | 12 | 12 | 0.0 | 0 | 0 |
| Eric Davis | DB | 10 | 10 | 0.0 | 0 | 0 |
| Mitch Donahue | LB | 9 | 9 | 0.0 | 0 | 0 |
| John Johnson | LB | 5 | 5 | 0.0 | 0 | 0 |
| Keith DeLong | LILB | 0 | 0 | 1.0 | 0 | 1 |
| Kevin Fagan | RDE | 0 | 0 | 2.0 | 0 | 0 |
| Larry Roberts | RDE | 0 | 0 | 7.0 | 0 | 1 |
| Dave Waymer | SS | 0 | 0 | 1.0 | 4 | 2 |