Franchise 77 seasons 609–519–14 all-time 30 playoff trips 5 Super Bowls
1992 players
Passing
| Steve Young | 402 | 268 | 3,465 | 25 | 7 | 8.6 |
| Steve Bono | 56 | 36 | 463 | 2 | 2 | 8.3 |
| Joe Montana | 21 | 15 | 126 | 2 | 0 | 6.0 |
| Keith Henderson | 1 | 1 | 36 | 1 | 0 | 36.0 |
| Ricky Watters | 1 | 0 | 0 | 0 | 0 | 0.0 |
Rushing
| Ricky Watters | 206 | 1,013 | 9 | 4.9 |
| Steve Young | 76 | 537 | 4 | 7.1 |
| Amp Lee | 91 | 362 | 2 | 4.0 |
| Tom Rathman | 57 | 194 | 5 | 3.4 |
| Keith Henderson | 44 | 150 | 1 | 3.4 |
| Jerry Rice | 9 | 58 | 1 | 6.4 |
| Marc Logan | 8 | 44 | 1 | 5.5 |
| Joe Montana | 3 | 28 | 0 | 9.3 |
| Steve Bono | 15 | 23 | 0 | 1.5 |
| John Taylor | 1 | 10 | 0 | 10.0 |
| Dexter Carter | 4 | 9 | 0 | 2.2 |
| Klaus Wilmsmeyer | 2 | 0 | 0 | 0.0 |
Receiving
| Jerry Rice | 139 | 84 | 1,201 | 10 | 8.6 |
| Brent Jones | 64 | 45 | 628 | 4 | 9.8 |
| Mike Sherrard | 59 | 38 | 607 | 0 | 10.3 |
| John Taylor | 35 | 25 | 428 | 3 | 12.2 |
| Ricky Watters | 52 | 43 | 405 | 2 | 7.8 |
| Tom Rathman | 55 | 44 | 343 | 4 | 6.2 |
| Odessa Turner | 17 | 9 | 200 | 2 | 11.8 |
| Ron Lewis | 31 | 13 | 152 | 0 | 4.9 |
| Amp Lee | 25 | 20 | 102 | 2 | 4.1 |
| Jamie Williams | 15 | 7 | 76 | 1 | 5.1 |
| Keith Henderson | 10 | 5 | 64 | 0 | 6.4 |
| Dexter Carter | 2 | 1 | 43 | 1 | 21.5 |
| Marc Logan | 2 | 2 | 17 | 0 | 8.5 |
Defense
| Dave Whitmore | SS | 100 | 100 | 0.0 | 1 | 2 |
| Bill Romanowski | ROLB | 80 | 80 | 1.0 | 0 | 1 |
| Merton Hanks | SS | 64 | 64 | 0.0 | 2 | 0 |
| Tim Harris | LOLB | 64 | 64 | 17.0 | 0 | 0 |
| Eric Davis | LCB | 61 | 61 | 0.0 | 3 | 1 |
| Don Griffin | RCB | 60 | 60 | 0.0 | 5 | 1 |
| Pierce Holt | LDE | 55 | 55 | 5.5 | 0 | 0 |
| Dana Hall | FS | 48 | 48 | 1.0 | 2 | 1 |
| Dennis Brown | DE | 36 | 36 | 3.5 | 1 | 0 |
| Ted Washington | NT | 35 | 35 | 2.0 | 0 | 0 |
| John Johnson | LB | 19 | 19 | 1.0 | 1 | 1 |
| Michael McGruder | DB | 19 | 19 | 0.0 | 0 | 0 |
| Antonio Goss | LB | 18 | 18 | 0.0 | 0 | 0 |
| Martin Harrison | LB | 12 | 12 | 3.5 | 0 | 1 |
| Alan Grant | DB | 11 | 11 | 0.0 | 0 | 0 |
| Kevin Fagan | RDE | 0 | 0 | 1.0 | 0 | 0 |
| Johnnie Jackson | DB | 0 | 0 | 1.0 | 0 | 0 |
| David Wilkins | LB | 0 | 0 | 1.5 | 0 | 1 |
| Larry Roberts | DE | 0 | 0 | 1.0 | 1 | 1 |
| Mike Walter | RILB | 0 | 0 | 1.0 | 0 | 3 |
| Michael Carter | NT | 0 | 0 | 1.0 | 0 | 1 |